What’s New in Osteoporosis and Fragility Fractures

Hansen, David V.; Tutaworn, Teerapat; Lane, Joseph M.

doi:10.2106/jbjs.22.00530

Cited by 6 publications

(3 citation statements)

References 54 publications

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“…The reader is encouraged to read the 2022 article, “What’s New in Osteoporosis and Fragility Fractures.” 1 This current article picks up where the last article ended and assumes that the reader is knowledgeable about the material covered previously.…”

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confidence: 99%

What’s New in Osteoporosis and Fragility Fractures

Lane

Witayakom

2023

Journal of Bone and Joint Surgery

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Update This article was updated on April 10, 2024, because of a previous error. On page 1304, the term “protein” that appeared incorrectly three times in the text that had read as “Their studies did reveal that metabolites from the protein pump inhibitor ingestion may directly and indirectly influence bone density through plasma metabolites involved in the sex hormone pathway. This article plus others have broadened the possible altered pathways related to protein pump inhibitor use. Regardless, these commonly used agents will compromise bone health. Clinicians should be alerted to this possibility when protein pump inhibitors are ingested.,” has now been replaced with the term “proton” so that the text now reads as “Their studies did reveal that metabolites from the proton pump inhibitor ingestion may directly and indirectly influence bone density through plasma metabolites involved in the sex hormone pathway. This article plus others have broadened the possible altered pathways related to proton pump inhibitor use. Regardless, these commonly used agents will compromise bone health. Clinicians should be alerted to this possibility when proton pump inhibitors are ingested.”

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What’s New in Osteoporosis and Fragility Fractures

Lane

Witayakom

2023

Journal of Bone and Joint Surgery

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“…However, a deficiency in this vitamin has a significant impact on the body. Vitamin D is most important for bone homeostasis and calcium metabolism 11,12 . When this vitamin is deficient, calcium cannot be absorbed.…”

Section: Shared Factors In the Etiopathogenesis Of Copd And Osteoporosismentioning

confidence: 99%

“…Supplementation with calcium and vitamin D is needed, along with regular monitoring of their levels in the blood and calcium in the urine. This approach effectively reduces the risk of osteoporosis and fractures 11,12 . The role of vitamin D extends to cellular proliferation, differentiation, and the regulation of the host's immune response.…”

Section: Shared Factors In the Etiopathogenesis Of Copd And Osteoporosismentioning

confidence: 99%

Chronic obstructive pulmonary disease and osteoporosis

Janković,

Buha,

Jandrić

et al. 2023

Galenika Med J

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Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by broncho-obstruction, loss of lung elasticity and parenchymal destruction. Today, this disease is the third cause of death in the world. Smoking is the main risk factor for this disease, while other risk factors are vitamin D deficiency, physical inactivity, and the use of systemic corticosteroids. Osteoporosis is a very common comorbidity in patients with COPD and is characterized by lower bone density and changes in the microarchitecture of the bone, which leads to fracture. These two diseases have the same pathophysiological mechanism of origin based on inflammation and common risk factors. If fractures occur, they can further worsen the already decreased pulmonary ventilation, reduce mobility and lead to disability. In patients with COPD it should be taken into consideration that there is a high likelihood of coexisting osteoporosis. Therefore, it is important to timely undertake appropriate diagnostic and preventative measures to prevent the progression of this condition

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