When and how does nonstructural mechanical prosthetic heart valve dysfunction occur?

Misawa, Yoshio; Saito, Tsutomu; Konishi, Hiroaki; Oki, Sadaaki; Kaminishi, Yuichiro; Takahashi, Hideki; Aizawa, Kei; Kamisawa, Osamu; Kato, Morito; Fuse, Katsuo

doi:10.1007/bf02719467

Cited by 18 publications

(15 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reported incidence of PVL after MVR varies from 5% to 32% [1][2][3][4]. It could occur early after MVR or newly develop late after MVR, even several years to a decade after surgery, without overt evidence of prosthetic valve endocarditis [5]. In the present study, early mitral PVL was recorded in only 1.9% of the patients, contrary to findings of previous studies that early PVL was detected in up to 32% of MVR patients [1,3].…”

Section: Commentcontrasting

confidence: 81%

“…The PVL can result from technical failure, which can be identified intraoperatively or by early postoperative echocardiography. It also occurs late after MVR, even several years to a decade after surgery, without any evidence of overt endocarditis [5]. The aims of this study were (1) to evaluate the incidence of early and late PVL, and (2) to analyze factors associated with PVL after MVR during more than 20 years of follow-up.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Paravalvular Leak After Mitral Valve Replacement: 20-Year Follow-Up

Hwang

Choi

Hyung-Kwan

et al. 2015

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

show abstract

Section: Commentcontrasting

confidence: 81%

mentioning

confidence: 99%

Paravalvular Leak After Mitral Valve Replacement: 20-Year Follow-Up

Hwang

Choi

Hyung-Kwan

et al. 2015

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

show abstract

“…5,6 The prosthetic valve orifi ce and the sewing cuff are designed to protect against pannus overgrowth on the valve. A pyrolite carbon coating and an orifi ce higher than the cuff material are effective in preventing pannus protrusion into the orifi ce, and pivot-guards also help prevent pannus from approaching and obstructing prosthetic valve pivots.…”

Section: Discussionmentioning

confidence: 99%

Starr-Edwards valves at the aortic and mitral positions implanted for 39 years

Misawa

Aizawa

Kaminishi

et al. 2011

Gen Thorac Cardiovasc Surg

Self Cite

View full text Add to dashboard Cite

Cloth-covered Starr-Edwards caged ball valves implanted in the aortic and mitral valve positions for 39 years were extracted. Both showed valve dysfunction resulting from pannus overgrowth. The metal cages of the Starr-Edwards valves were covered with worn cloth. This case indicates the extended durability of Starr-Edwards valves and the importance of the design and materials of prosthetic heart valves to avoid pannus overgrowth and prosthetic valve abrasion.

show abstract

“…Thrombosed prosthetic valves, pannus formation restricting prosthetic valve function, and paravalvular leaks with or without overt infective endocarditis can result in reoperation. 10 The linearized rate of mechanical valve thrombosis is between 0.04 and 0.39% per patient-year. [11][12][13][14][15] Paravalvular leaks occur at a rate of 0.1-0.92% per patientyear, [15][16][17] and endocarditis at 0.1-0.53% per patient-year.…”

Section: Discussionmentioning

confidence: 99%

Twenty-Two Year Experience with the Omniscience Prosthetic Heart Valve

Misawa¹,

Taguchi²,

Aizawa³

et al. 2004

ASAIO Journal

Self Cite

View full text Add to dashboard Cite

This study was designed to evaluate the long-term clinical results of the Omniscience tilting disc valve. Omniscience valves were implanted in 51 patients (mean age, 50 +/- 10 years); 18 had aortic valve, 24 had mitral valve, and 9 had both aortic and mitral valve replacements. Oral warfarin potassium and dipyridamole were prescribed as our anticoagulant therapy. Preoperatively, 42 patients were in New York Heart Association class III or IV, and 23 of 25 surviving patients were in class I or II after operation. There were 2 (3.9%) early deaths and 23 late deaths (3.5 +/- 0.7% per patient-year). Cardiac related mortality including congestive heart failure, sudden death, and thromboembolism, and hemorrhagic complications were seen in 16 patients. Overall survival at 10, 15, and 20 years was 77 +/- 6%, 62 +/- 7%, and 46 +/- 7%, respectively. Thromboembolic complications were seen in 5 patients, for a rate of 0.8 +/- 0.3% per patient-year; similarly, hemorrhagic complications were also seen in 5 patients. Nonstructural prosthetic valve dysfunction was seen in 4 patients, for a rate of 0.6 +/- 0.3% per patient-year, and sudden death was seen in 2, a rate of 0.3 +/- 0.2% per patient-year. The Omniscience prosthesis demonstrated excellent postoperative clinical status with low rates of valve related complications.

show abstract

When and how does nonstructural mechanical prosthetic heart valve dysfunction occur?

Abstract: Paravalvular leaks without overt endocarditis had latency periods of up to 12 years, and pannus formation was observed 20 years after surgery. Early and late clinical results after surgery for mechanical valve dysfunction were excellent.

Cited by 18 publications

References 22 publications

Paravalvular Leak After Mitral Valve Replacement: 20-Year Follow-Up

Paravalvular Leak After Mitral Valve Replacement: 20-Year Follow-Up

Starr-Edwards valves at the aortic and mitral positions implanted for 39 years

Twenty-Two Year Experience with the Omniscience Prosthetic Heart Valve

Contact Info

Product

Resources

About