When is it necessary to perform nuclear renogram in patients with a unilateral neonatal hydronephrosis?

Burgu, Berk; Aydoğdu, Özgü; Soygür, Tarkan; Baker, Linda A.; Snodgrass, Warren; Wilcox, Duncan T.

doi:10.1007/s00345-011-0744-6

Cited by 12 publications

(9 citation statements)

References 21 publications

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“…They predicted that the mean APD in resolved cases was \10 mm [1]. Burgu et al suggested that DRF is preserved (C40 %) when APD is \20 mm [15]. Our results were also concordant with the results of these studies.…”

Section: Resultssupporting

confidence: 95%

Correction of differential renal function for asymmetric renal area ratio in unilateral hydronephrosis

Aktaş

Sarıkaya

2015

Ann Nucl Med

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Section: Resultssupporting

confidence: 95%

Correction of differential renal function for asymmetric renal area ratio in unilateral hydronephrosis

Aktaş

Sarıkaya

2015

Ann Nucl Med

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“…42–44 In addition, individuals with VACTERL association frequently have GU anomalies. 45 Physical examination may yield findings warranting further medical/surgical interventions.…”

Section: Suggested Diagnostic Approachmentioning

confidence: 99%

An Approach to the Identification of Anomalies and Etiologies in Neonates with Identified or Suspected VACTERL (Vertebral Defects, Anal Atresia, Tracheo-Esophageal Fistula with Esophageal Atresia, Cardiac Anomalies, Renal Anomalies, and Limb Anomalies) Association

Solomon¹,

Baker²,

Bear³

et al. 2014

The Journal of Pediatrics

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“…Only a few studies showed that giant hydronephrosis could be asymptomatic until the late stage (17), or only manifests with non-specific symptoms (18), such as fatigue or indigestion. The incidence of asymptomatic hydronephrosis among newborns is 0.5% to 1% (19), and the incidence of central DI is 3-4 patients per 100,000 (20). As asymptomatic hydronephrosis is more common, we should pay special attention to it when it is accompanied by DI, other nephrologic disorders or symptoms (increased water intake, strenuous exercise or urinary retention).…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic obstructive hydronephrosis associated with diabetes insipidus: a case report and review

Sun¹,

Zhao²,

Zhu³

et al. 2021

Transl Pediatr

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The treatment of asymptomatic hydronephrosis due to ureteropelvic junction obstruction (UPJO), as well as the timing and indications for surgical intervention, remain controversial. Diabetes insipidus (DI) is a rare disease in infants that is known to cause non-obstructive hydronephrosis, while its association with obstructive hydronephrosis has not been reported. Some studies have found that increased water intake is a predisposing risk factor of developing hydronephrosis. However, there are no studies or guidelines that indicate the specific follow-up intervals and surgical indications for mild hydronephrosis if predisposing risk factors persist. A 46-month-old boy was admitted to our Urology Department with a history of Society of Fetal Urology (SFU) Grade 2 prenatal left hydronephrosis, which was stable at SFU Grade 1-2 at regular postnatal follow-ups. The patient developed polydipsia and polyuria three months prior to admission, then he was considered as primary polydipsia by endocrinology and was treated with fluid restriction while the examination was negative. Renal ultrasound at follow-up demonstrated severe left hydronephrosis with an anterior-posterior diameter (APD) of 6.25 cm three months after symptom onset. Diuretic renography (DR) revealed a renal function of 13.7% with a glomerular filtration rate (GFR) of 11.25 mL/min. The patient was otherwise asymptomatic without any abdominal pain or vomiting. He underwent left pyelostomy immediately as well as laparoscopic left dismembered ureteropelvioplasty after three months, and a diagnosis of UPJO was confirmed. The patient had an uncomplicated postoperative recovery and the result of follow-up renal ultrasound was stable. However, the symptoms of polydipsia and polyuria did not improve significantly. He underwent pituitary magnetic resonance imaging (MRI) and pathological examination, the results of which were consistent with central DI caused by Langerhans cell hyperplasia four months postoperatively. This case indicates the need to pay attention to children with mild hydronephrosis undergoing regular observation and conservative treatment, as a sudden aggravation of the hydronephrosis and a rapid decline of renal function may occur if DI persists.

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When is it necessary to perform nuclear renogram in patients with a unilateral neonatal hydronephrosis?

Cited by 12 publications

References 21 publications

Correction of differential renal function for asymmetric renal area ratio in unilateral hydronephrosis

Correction of differential renal function for asymmetric renal area ratio in unilateral hydronephrosis

An Approach to the Identification of Anomalies and Etiologies in Neonates with Identified or Suspected VACTERL (Vertebral Defects, Anal Atresia, Tracheo-Esophageal Fistula with Esophageal Atresia, Cardiac Anomalies, Renal Anomalies, and Limb Anomalies) Association

Asymptomatic obstructive hydronephrosis associated with diabetes insipidus: a case report and review

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