Where are we with coronary artery disease for the cyanotic patient with congenital heart disease?

Segura, T

doi:10.1016/j.ijcard.2018.10.033

Cited by 9 publications

(8 citation statements)

References 8 publications

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“…In our study, out of a total of 200 cases, ACHDs constituted 142 cases accounting for 71% of total CHDs, which is similar to other studies [ 11 - 14 ]. CCHDs constituted 58 cases accounting for 29% of all CHD cases, which is similar to previously reported studies [ 15 - 18 ]. In our study, the male-to-female ratio was 1.8, which is similar to the study by Hussain and Kumar et al [ 10 , 12 ].…”

Section: Discussionsupporting

confidence: 90%

Clinical and Echocardiographic Profile of Congenital Heart Diseases in the 0-12-Year Age Group in a Tertiary Care Medical Institute in Eastern India: A Retrospective, Cross-Sectional Study

Kishore¹,

Kumar²,

Kumar³

et al. 2022

Cureus

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Background This study aimed to determine the clinical and echocardiography profile of congenital heart diseases (CHDs) among admitted children as well as patients presenting to the outpatient department of the Indira Gandhi Institute of Medical Sciences, Patna, which is a tertiary care and apex institute located in Bihar, India. Methodology A retrospective, cross-sectional study was conducted in a tertiary care hospital from January 2019 to January 2021. In total, 200 patients aged 0-12 were enrolled in the study. The study design was exploratory, with a proforma drafted to study patients with features suggestive of CHDs. All pediatric echocardiography was performed by a trained cardiologist. Records were obtained from the departmental record-keeping register, and reports were available for analyzing the data. For data collection, cardiology and pediatric department registers were reviewed and all CHD data were collected. Data analysis was done using SPSS software version 25.0 (IBM Corp., Armonk, NY, USA). Results Of the 200 children with CHDs, 142 were diagnosed to have acyanotic heart disease (ACHD), while 58 had cyanotic congenital heart disease (CCHD). Among 200 cases of CHD, ventricular septal defect (VSD) constituted 62 cases comprising 31% of the total CHD cases and 44% of all ACHD cases. Atrial septal defect (ASD) was the second most common CHD comprising 23% of all CHD cases. Tetralogy of Fallot (TOF) constituted 23 cases accounting for 11.5% of all CHD cases. It was the most common CCHD. Based on the age at the time of presentation, 90 (45%) cases were diagnosed below one year of age. Congestive heart failure (CHF) was most common in ACHD comprising 30% compared to CCHD in which only 7% of cases had CHF. This finding was statistically significant (p < 0.05). Analyzing the symptoms of different CHDs, of both ACHDs and CCHDs, the common symptoms were fast breathing (38%). Conclusions Among ACHD patients, 31% VSD and 21% ASD were noted. In CCHD, TOF was the most common with 11.5% of cases. Respiratory tract conditions were the most common comorbidities encountered. Because this is one of the first studies conducted in Bihar in the pediatric age group, it can help know the prevalence of CHDs in this region and will be useful for developing policies by stakeholders.

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Section: Discussionsupporting

confidence: 90%

Clinical and Echocardiographic Profile of Congenital Heart Diseases in the 0-12-Year Age Group in a Tertiary Care Medical Institute in Eastern India: A Retrospective, Cross-Sectional Study

Kishore¹,

Kumar²,

Kumar³

et al. 2022

Cureus

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“…The most prevalent birth defect and the main factor in the death of children with congenital abnormalities is CHD (1) . Noncyanotic CHD and cyanotic CHD, commonly known as critical congenital heart disease are two subtypes of CHD (2) .…”

Section: Introductionmentioning

confidence: 99%

“…Cyanotic congenital heart disease (CCHD) is congenital heart also defect with right to left shunting of desaturated blood. This results in decreased oxygen saturation in the systemic circulation which acts as a trigger for increase in erythropoietin production and secondary erythropoiesis in an effort to maintain tissue oxygenation (2) . The resultant polycythemia and hyperviscosity manifests clinically as thromboembolic events in the children with CCHD (6) .…”

Section: Introductionmentioning

confidence: 99%

Iron Deficiency in Children with Cyanotic and Noncyanotic Congenital Heart Disease

Elmoghazy¹,

Ibrahim²,

Abdulnabi³

et al. 2022

The Egyptian Journal of Hospital Medicine

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Background: Cyanotic congenital heart disease (CCHD) predisposes patients to iron deficiency due to compensatory secondary erythrocytosis. Objective: This study aimed to assess the prevalence of iron deficiency among infants and children having cyanotic and non-cyanotic congenital heart disease. Patients and methods: This was a case-control study enrolled 30 children with congenital heart disease whether cyanotic or non-cyanotic at the

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“…CHD is of two types, non-cyanotic CHD and cyanotic CHD (CCHD), also called critical congenital heart disease (CCHD) (Galvis et al, 2020). CCHD is additionally subclassi ed into 3 different types of lesions: right heart obstructive lesions, left heart obstructive lesions, and mixing lesions (Desai et al, 2019& Segura et al, 2019& Mohammad et al, 2019& Schaan et al,2019as cited by Galvis, 2020). More females (1,260,000) have a mild margin than males (1,163,000) living with a CHD in the USA.…”

Section: Introductionmentioning

confidence: 99%

Association between maternal race and the occurrence of cyanotic congenital heart disease in the USA

Ebeh

Jahanfar

2021

Preprint

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Introduction Overall mortality due to congenital heart disease in the United States declined between 1999 and 2017. However, disparities still exist in occurrence and mortality rates among specific racial/ethnic groups in the USA. Objective This study aims to find the association between maternal race and the occurrence of Cyanotic Congenital Health Disease (CCHD) in the USA. Methods We carry out analysis on a secondary dataset (2017 Natality) obtained from the US Centers for Disease Control and Prevention. This was analyzed using descriptive, bivariate, and regression analysis. This cross-sectional study obtained socio-demographic information-maternal race, independent and confounder variables (explanatory variables), and the occurrence of Cyanotic Congenital Health Disease (outcome variable) within the reporting States and U.S. territories. Result There was a report of 3,864,754 live birth out of 325,719,178 USA races and origin populations for the 2017 review year. A total number of 2130 CCHD birth was reported to have occurred out of the 3,8161,947 live births. The Chi-square test showed a statistically significant association between maternal race and the occurrence of CCHD. As well as, the following confounders mother's age, mother's nativity, combined gestation, pre-pregnancy diabetes, pre-pregnancy hypertension, month prenatal care began, smoking status, and Nutrition (WIC) all having a p-value of 0.01 each, respectively. Unadjusted odds ratios at 95 % CI of the association between maternal race and CCHD were 56 % higher among American Indian and Alaska Native women (95% CI 1.13-2.15) than the white racial group. In addition, the Odds were 13% (95% CI 0.78-0.98) and 46% (95% CI 0.43-0.66) less likely amongst Black and Asian or Pacific Islander, respectively. The odds were 402% markedly high for pre-pregnancy diabetes, 159% for pre-pregnancy hypertension, 38 % for smoking status, and 44%, 159%, and 42% respectively for prenatal care from 1st to 2nd months, 4th to 6th months, and 7th to the final month, when compared to no prenatal care. The odds of having a CCHD was 16% less likely for mothers on Nutrition (mothers on WIC) (95% CI 0.77-0.92), 19% (95% CI 0.73-0.90) for mothers age (under 35 years) category, and likewise for mothers born outside of the USA at 39% (95% CI 1.22-1.56). On Adjustment for confounders, the OR for this relationship was on the higher side for many of the variables. The odds of occurrence of CCHD were 59 % higher among Black (95% CI 1.27-2.0), 35% among AIAN (95 % CI 1.05-1.74), and 92 % among American Indian and Alaska Native (95 % CI 1.26-2.93) racial categories when compared to Asian or Pacific Islander categories. The odds of having a CCHD was also elevated on adjustment for mothers born outside of the USA at 39% (95% CI 1.22-1.56), and at from the 7th to final month 94% (95% CI 1.38-2.73). However, the odds were insignificant in other categories and variables. These estimates suggest the occurrence of a CCHD is associated with the analyzed independent predictor and confounder variables. Conclusion An association exists between maternal race and the occurrence of cyanotic congenital heart disease in the USA. Further research in this area, may therefore help to diminish the occurrence, morbidity, and or mortality of CCHD in America and globally as well. Keywords: Association, maternal race, cyanotic congenital heart disease, USA

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Where are we with coronary artery disease for the cyanotic patient with congenital heart disease?

Cited by 9 publications

References 8 publications

Clinical and Echocardiographic Profile of Congenital Heart Diseases in the 0-12-Year Age Group in a Tertiary Care Medical Institute in Eastern India: A Retrospective, Cross-Sectional Study

Clinical and Echocardiographic Profile of Congenital Heart Diseases in the 0-12-Year Age Group in a Tertiary Care Medical Institute in Eastern India: A Retrospective, Cross-Sectional Study

Iron Deficiency in Children with Cyanotic and Noncyanotic Congenital Heart Disease

Association between maternal race and the occurrence of cyanotic congenital heart disease in the USA

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