Which obesity index is the best predictor for high cardiovascular disease risk in middle-aged and elderly population?

Chang, Kai-Ting; Chen, Chih‐Hao; Chuang, Hai‐Hua; Tsao, Yu-Chung; Lin, Yu‐Jr; Lin, Pu; Chen, Yun-Hung; Yeh, Wen‐Ling; Tzeng, I‐Shiang; Chen, Jau-Yuan

doi:10.1016/j.archger.2018.06.002

Cited by 17 publications

(11 citation statements)

References 24 publications

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“…There are a number of potential biological mechanisms to explain the relation between weight cycling and CVH metrics. Weight cycling may contribute to CVD risk by leading to preferential deposition of visceral fat (Chang et al, 2018) or perivascular adipose tissue, (Costa et al, 2018) which are more strongly associated with CVD risk. The biological mechanisms behind preferential fat deposition are not fully elucidated in humans, (Montani et al, 2006) but there are studies showing preferential changes in body composition after weight regain may be due to metabolic adaptation or slowing of resting metabolic rate.…”

Section: Discussionmentioning

confidence: 99%

Associations of weight cycling with cardiovascular health using American Heart Association’s Life’s Simple 7 in a diverse sample of women

Byun

Bello

Liao

et al. 2019

Preventive Medicine Reports

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Section: Discussionmentioning

confidence: 99%

Associations of weight cycling with cardiovascular health using American Heart Association’s Life’s Simple 7 in a diverse sample of women

Byun

Bello

Liao

et al. 2019

Preventive Medicine Reports

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“…Individuals with obesity often suffer from lipid metabolism disorder[69], which leads to increase risk of CVD[70]. Exercise is especially known as an economic and effective approach to reduce fat accumulation, however, the results of this review comparisons of HIIT and MICT interventions revealed no significant differences in their effects on TG, TC, LDL, HDL.…”

Section: Discussionmentioning

confidence: 95%

Effects of HIIT and MICT on cardiovascular risk factors in adults with overweight and/or obesity: A meta-analysis

et al. 2019

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ObjectiveThe purpose of this study was to evaluate the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on cardiovascular disease (CVD) risk factors in adults with overweight and obesity.MethodsTwenty-two articles were included by searching six databases, the total number of subjects was 620 in these articles. Outcomes were synthesised using a random-effects meta-analysis of the Standardized mean difference (SMD) in CVD risk factors.ResultsHIIT and MICT resulted in statistically significant reductions in Weight, BMI, fat%, total cholesterol(TC), and improvement in VO2max. Compared with MICT, subgroup of durations of HIIT training interval ≥2 min can significantly increase VO2max (SMD = 0.444, 95% CI:0.037~0.851,P = 0.032), subgroup of energy expenditure of HIIT equal to MICT can significantly increase VO2max (SMD = 0.399, 95% CI:0.106~0.692,P = 0.008).ConclusionsHIIT appears to provide similar benefits to MICT for improving body composition, VO2maxand TC, but HIIT spent less time than MICT by 9.7 min on one session. HIIT is superior to MICT in improving cardiopulmonary fitness when durations of HIIT training interval ≥2 min or energy expenditure of HIIT same as MICT. PROSPERO ID: CRD42016045835.

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“…Different obesity indices show different comorbidity risks. WC is more strongly associated with a high risk of cardiovascular disease (CVD) than BMI among middle-aged and elderly persons in Taiwan 4 5. BMI and WC are more positively correlated with insulin resistance than BF percentage 6…”

Section: Introductionmentioning

confidence: 99%

Relationship between obesity indices and hypertension among middle-aged and elderly populations in Taiwan: a community-based, cross-sectional study

et al. 2019

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ObjectiveObesity and hypertension (HTN) have become increasingly prevalent in Taiwan. People with obesity are more likely to have HTN. In this study, we evaluated several anthropometric measurements for the prediction of HTN in middle-aged and elderly populations in Taiwan.DesignCross-sectional observational study.SettingCommunity-based investigation in Guishan Township of northern Taiwan.ParticipantsA total of 396 people were recruited from a northern Taiwan community for a cross-sectional study. Anthropometrics and blood pressure were measured at the annual health exam. The obesity indices included body mass index (BMI), body fat (BF) percentage and waist circumference (WC).Outcome measuresStatistical analyses, including Pearson’s correlation, multiple logistic regression and the area under ROC curves (AUCs) between HTN and anthropometric measurements, were used in this study.ResultsOf the 396 people recruited, 200 had HTN. The age-adjusted Pearson’s coefficients of BMI, BF percentage and WC were 0.23 (p<0.001), 0.14 (p=0.01) and 0.26 (p<0.001), respectively. Multiple logistic regression of the HTN-related obesity indices showed that the ORs of BMI, BF percentage and WC were 1.15 (95% CI 1.08 to 1.23, p<0.001), 1.07 (95% CI 1.03 to 1.11, p<0.001) and 1.06 (95% CI 1.03 to 1.08, p<0.001), respectively. The AUCs of BMI, BF percentage and WC were 0.626 (95% CI 0.572 to 0.681, p<0.001), 0.556 (95% CI 0.500 to 0.613, p=0.052) and 0.640 (95% CI 0.586 to 0.694, p<0.001), respectively.ConclusionsWC is a more reliable predictor of HTN than BMI or BF percentage. The effect of abdominal fat distribution on blood pressure is greater than that of total BF amount.

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Which obesity index is the best predictor for high cardiovascular disease risk in middle-aged and elderly population?

Abstract: VFR and WC were more strongly associated with high CVD risk than BMI among middle-aged and elderly persons in Taiwan.

Cited by 17 publications

References 24 publications

Associations of weight cycling with cardiovascular health using American Heart Association’s Life’s Simple 7 in a diverse sample of women

Associations of weight cycling with cardiovascular health using American Heart Association’s Life’s Simple 7 in a diverse sample of women

Effects of HIIT and MICT on cardiovascular risk factors in adults with overweight and/or obesity: A meta-analysis

Relationship between obesity indices and hypertension among middle-aged and elderly populations in Taiwan: a community-based, cross-sectional study

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