Whole Body Dwibs Mri Versus Bone Scan for Evaluating Skeletal Metastases

Gandage, Siddappa Gurubalappa; Kachewar, Sushil; Aironi, Vinayak Dattatray; Nagapurkar, Abhijeet Devidas

doi:10.21767/amj.2012.1500

Cited by 9 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar results were reported by Gandage SG. et al [30] and Kachewar SG [31]. While in detection of metastatic extra-osseous lesions, its sensitivity was 94.4% with positive predictive value = 97.5%.…”

Section: Discussionmentioning

confidence: 99%

Accuracy and diagnostic value of diffusion-weighted whole body imaging with background body signal suppression (DWIBS) in metastatic breast cancer

Eissawy

Saadawy

Farag

et al. 2021

Egypt J Radiol Nucl Med

View full text Add to dashboard Cite

Background Breast cancer is the most common malignant tumor among women. The mortality of the patients could be mainly attributed to metastasis and spread of breast cancer to distant sites. The objective of the current study is to evaluate and express the role of diffusion-weighted whole body imaging with background body signal suppression (DWIBS) in detection of osseous and soft tissue metastatic lesions in patients with cancer breast. Results The current prospective study included 50 female patients with pathologically proven breast cancer. The overall sensitivity of DWIBS and STIR were 97.5% and 92.5%, respectively. DWIBS was the most sensitive sequence with highest negative predictive values. DWIBS and STIR were the most sensitive with the highest negative predictive value. Both DWIBS and STIR detected more vertebral metastatic deposits (100% and 97.8%, respectively) and more soft tissue lesions (94.4% for both) than WB DWI and T1WI. Conclusion DWIBS MRI sequence is an effective method for detection of solid organ, bone and lymph node metastasis but not specific for characterization of lesions.

show abstract

Section: Discussionmentioning

confidence: 99%

Accuracy and diagnostic value of diffusion-weighted whole body imaging with background body signal suppression (DWIBS) in metastatic breast cancer

Eissawy

Saadawy

Farag

et al. 2021

Egypt J Radiol Nucl Med

View full text Add to dashboard Cite

show abstract

“…In an attempt to reduce unnecessary gadolinium application, especially in patients that receive multiple WB-MRI as part of surveillance or therapy-response protocols, whole-body diffusion weighted imaging (WB-DWI) with apparent diffusion coefficient maps (ADC) has been suggested as an effective alternative to the contrasted sequences [29,30]. Previous studies report a high diagnostic accuracy for WB-DWI either as stand-alone [31,32] or as protocol addition to T1w and STIR sequences for the differentiation between malignant and benign lesions [26,33]. In conclusion, there is increasing evidence towards replacement of gadolinium with WB-DWI sequences for the diagnosis of osseous metastasis either for the first diagnostic or in follow up settings.…”

Section: Discussionmentioning

confidence: 99%

Whole body MRI for Breast Cancer Staging: the roles of the Field Strength and Gadolinium Contrast Agents in Focus

Wiech¹,

Peix²,

Predel³

et al. 2018

Madridge J Oncogenesis

View full text Add to dashboard Cite

Purpose: Whole-body magnetic resonance imaging (WB-MRI) is emerging as a powerful diagnostic tool for breast cancer staging, especially for the detection of bone metastasis. However there is a low level of evidence concerning the added benefit from the use of higher field strengths and contrast agents. In this study we compare the diagnostic efficacy of WB-MRI for the field strengths 1.5T and 3T commonly used in the clinic. Moreover, we investigate the added benefit from gadolinium contrast agent application towards the effective detection of breast cancer bone metastasis. Methods and Materials:The study was retrospective for 855 patients scanned between 05/2007 and 08/2017. 345 patients were imaged at 1.5T and 510 at 3T field strength (Philips Achieva or Ingenia) with a T1w FFE and a STIR or a Dixon at the coronal orientation. In 431 patients we injected gadoteridol (ProHance®) 0.1 mmol/kg. Clinical confirmation with skeletal scintigraphy or bioptic confirmation served as the ground truth. Results:The sensitivity (SE) and specificity (SPE) for 1.5T were 98.34%/91.24% and the positive predictive value (PPV)/negative predictive value (NPV) were 86.03%/99%. A field strength of 3T showed SE/SPE of 100%/92.81% and PPV/NPV of 83.22%/100%. Binary logistic regression with Fisher´s exact test revealed no significant difference between 1.5T and 3T WB-MRI (P 0.663, odds ratio 0.839). The SE/SPE of WB-MRI (merged 1.5T and 3T) without enhancement were 98.66% 91/60%, with PPV/NPV 86.54%/99.20%. Upon administration of contrast agent, the SE/SPE shifted to 100%/92.83% and the PPV/NPV to 82.70%/100%. Binary logistic regression with Fisher´s exact test returned no significant effect for the contrast agent (P 0.836, odds ratio 0.9). Conclusion:WB-MRI is a highly specific and sensitive diagnostic tool for bone metastasis in breast cancer with equal diagnostic efficacy in the field strengths of 1.5T or 3T. Gadolinium can be omitted without affecting the diagnostic accuracy and its usage should be spared only for problem-solving.

show abstract

“…Combined use of DWI and WB-MRI improves the accuracy of detection and characterization of lesions, and studies have also shown the WB-DWI has higher diagnostic sensitivity than bone scintigraphy in various types of malignancy. 27,28 Interpretation of abnormal high signals in bone and benign bone conditions, including red bone marrow, fractures, infarction, inflammation and benign tumors, using DWI can lead to false positive diagnosis of bone metastasis. 17,29 Red bone marrow might be the most problematic in terms of these false positives, because the signals from bone metastasis and red bone marrow are very similar on STIR and T1WI, as well as on DWI.…”

Section: Application Of Dwi In Detecting Bone Metastasismentioning

confidence: 99%

Whole‐body diffusion‐weighted magnetic resonance imaging: Diagnosis and follow up of prostate cancer and beyond

Yoshida¹,

Takahara

Arita³

et al. 2021

Int J of Urology

View full text Add to dashboard Cite

Abbreviations & Acronyms ADC = apparent diffusion coefficient ADT = androgen deprivation therapy CRPC = castration-resistant prostate cancer CT = computed tomography DWI = diffusion-weighted imaging DWIBS = diffusion-weighted whole-body imaging with background body signal suppression MET-RADS-P = METastasis Reporting and Data System for Prostate Cancer MIP = maximum intensity projection MRI = magnetic resonance imaging PET = positron emission tomography PSA = prostate-specific antigen PSMA = prostate-specific membrane antigen SPECT = single-photon emission computed tomography STIR = short-tau inversion recovery T1WI = T1-weighted imaging T2WI = T2-weighted imaging USPIO = ultrasmall superparamagnetic iron oxide WB-DWI = whole-body diffusion-weighted imaging

show abstract

Whole Body Dwibs Mri Versus Bone Scan for Evaluating Skeletal Metastases

Cited by 9 publications

References 0 publications

Accuracy and diagnostic value of diffusion-weighted whole body imaging with background body signal suppression (DWIBS) in metastatic breast cancer

Accuracy and diagnostic value of diffusion-weighted whole body imaging with background body signal suppression (DWIBS) in metastatic breast cancer

Whole body MRI for Breast Cancer Staging: the roles of the Field Strength and Gadolinium Contrast Agents in Focus

Whole‐body diffusion‐weighted magnetic resonance imaging: Diagnosis and follow up of prostate cancer and beyond

Contact Info

Product

Resources

About