Whole Body Measurements of 131I-Tetracycline as an Index of Skeletal Growth

Wolfangel, Robert G.; Shaw, Stanley M.; Christian, John E.

doi:10.1002/jps.2600590406

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Direct Electrophilic Halogenation1

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1979

1983

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Cited by 2 publications

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“…As succinimide can be regarded as a strong acid, an approach similar to eq. 16 has been applied for radioiodination using the silver salt of succinimide and molecular iodine [219,220], Concerning the hypohalites, the perfluorinated Nchloro compound has been prepared [43] according to the procedure for the N-bromo compound [221], and successfully used for the in-situ radiobromination [222] and radioiodination [213] of activated and deactivated aromatic compounds. With toluene as a model compound in trifluoroacetic anhydride at room temperature, an n.c.a.…”

Section: Direct Electrophilic Halogenationmentioning

confidence: 99%

No-Carrier-Added Radiohalogenation Methods with Heavy Halogens

1983

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Radiolabeling methods with the heavy halogens bromine, iodine and astatine are reviewed. The methods are evaluated on the basis of their underlying chemical principles and their usefulness for the no-carrier-added labeling of biologically-useful compounds. Special emphasis is placed on the stability, specific activity, and quality control of radiohalogenation products using the shortlived, neutron-deficient nuclides 7s ' 7 'Br, '"I, and 2 "At in view of their importance as radiopharmaceuticals.

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Section: Direct Electrophilic Halogenationmentioning

confidence: 99%