Whole-body MRI as a screening tool?

Ladd, Susanne C.

doi:10.1016/j.ejrad.2009.02.011

Cited by 23 publications

(24 citation statements)

References 61 publications

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“…The most common incidental lesions in the WB-MRI examinations were renal cysts [17], liver hemangiomas [13], liver cysts [12], thyroid nodules [8], and uterine leiomyomas (5). Also, two adrenal gland adenomas were seen.…”

Section: Resultsmentioning

confidence: 99%

Whole-Body MRI Screening in Asymptomatic Subjects; Preliminary Experience and Long-Term Follow-Up Findings

et al. 2016

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SummaryBackgroundThe aim of this study is to describe the technique and to evaluate the results of whole-body magnetic resonance imaging in an asymptomatic population.Material/MethodsBetween March 2009 and December 2011, 118 consecutive subjects undergoing thorough medical check-up were prospectively included in the study. MRI was performed with a 205-cm moving table, parallel imaging and automatic image composing software.ResultsIn 83 subjects (70%), 103 benign lesions were detected. Two malignant (adrenal and renal carcinoma) lesions and one precancerous (pancreatic mucinous carcinoma) lesion were detected. The most common lesions were renal cysts, liver hemangiomas, liver cysts, thyroid nodules, and uterine leiomyomas.ConclusionsWB-MRI is able to cover area from head to toes in one diagnostic work-up, and besides the anatomic regions evaluated by conventional radiological modalities, i.e. brain parenchyma, bones and extremities, can be evaluated in one examination.

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Section: Resultsmentioning

confidence: 99%

Whole-Body MRI Screening in Asymptomatic Subjects; Preliminary Experience and Long-Term Follow-Up Findings

et al. 2016

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“…It is expected that the study results will be applicable to clinical practice through identification of novel imagingbased biomarkers that enable us to best predict individual risk. To date, evidence on whole-body MR imaging as a disease screening modality is limited and has been associated with overdiagnosis and risk of false-positive findings (55) while its clinical value in the diagnosis of systemic oncologic or inflammatory diseases is more established (56). In the setting of such large studies, the obtained high-contrast imaging information will be primarily used to assess the prevalence of subclinical disease states and normal variants and to understand pathophysiologic pathways in the natural history of disease development, but it will also be used to identify novel imaging biomarkers of risk due to the longitudinal study design.…”

Section: Discussionmentioning

confidence: 99%

Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background

Bamberg¹,

et al. 2015

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“…For MR imaging, there has been a recent introduction of whole-body imaging units, which use a system of multiple phased-array coils covering the entire body. The result is a combination of dedicated assessment of various organs by means of sequences with adequate soft-tissue contrast and spatial resolution and of whole-body anatomic coverage (68,69).…”

Section: Role Of Imaging Controversies and Current Recommendationsmentioning

confidence: 99%

Imaging of Cancer Predisposition Syndromes in Children

Monsalve¹,

Kapur²,

Malkin³

et al. 2011

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The term cancer predisposition syndrome (CPS) encompasses a multitude of familial cancers in which a clear mode of inheritance can be established, although a specific gene defect has not been described in all cases. Advances in genetics and the development of new imaging techniques have led to better understanding and early detection of these syndromes and offer the potential for preclinical diagnosis of any associated tumors. As a result, imaging has become an essential component of the clinical approach to management of CPSs and the care of children suspected of having a CPS or with a confirmed diagnosis. Common CPSs in children include neurofibromatosis type 1, Beckwith-Wiedemann syndrome, multiple endocrine neoplasia, Li-Fraumeni syndrome, von Hippel-Lindau syndrome, and familial adenomatous polyposis. Radiologists should be familiar with these syndromes, their common associated tumors, the new imaging techniques that are available, and current screening and surveillance recommendations to optimize the assessment of affected children.

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Whole-body MRI as a screening tool?

Cited by 23 publications

References 61 publications

Whole-Body MRI Screening in Asymptomatic Subjects; Preliminary Experience and Long-Term Follow-Up Findings

Whole-Body MRI Screening in Asymptomatic Subjects; Preliminary Experience and Long-Term Follow-Up Findings

Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background

Imaging of Cancer Predisposition Syndromes in Children

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