Whole Body MRI for Detecting Metastatic Bone Tumor: Comparison with Bone Scintigrams

Abstract

Purpose: To compare the eŠectiveness of whole body MRI (WB-MRI [magnetic resonance imaging]) and bone scintigram (BS) at detecting bone metastasis.Materials and Methods: WB-MRI was performed on 16 patients for detecting bone metastasis (6 breast carcinoma, 7 prostatic carcinoma, 1 renal cell carcinoma [RCC], 1 hepatocellular carcinoma [HCC], and 1 primary unknown). BS was also performed in all cases. Patients were placed on a table top extender (Philips Medical Systems). The maximal longitudinalˆeld of view (FOV) was 200 cm. Atˆrst, the total spine was imaged in the sagittal plane with a three-station approach for two image sets (fast spin-echo [SE] T 1 -weighted images [T 1 WI] and short tau inversion recovery [STIR] images). The whole body was then imaged in the coronal plane with a seven-station approach for two image sets (fastˆeld echo [FFE] T 1 WI and STIR). Total examination time, including patient positioning, was within 40 min. Three independent radiologists interpreted the imaging data.Results: WB-MRI identiˆed 5 cases of 24 lesions as bone metastasis, while BS identiˆed 3 cases of 25 lesions. Concordance between WB-MRI and BS was seen in 3 cases of 22 lesions (81z). For two cases of 2 lesions, which were identiˆed only with WB-MRI, the lesions were located in the sacrum and thoracic spine. For one case of 3 lesions, which was identiˆed only with BS, the lesions were located in the skull and rib.Conclusion: WB-MRI was an excellent method for screening bone metastasis, especially the vertebral body.

Diagnostic value of whole‐body magnetic resonance imaging for bone metastases: a systematic review and meta‐analysis

“…In the selected 11 studies, four studies conducted WB-MRI with DWI (22,27,(29)(30). The other studies conducted WB-MRI without DWI; seven studies used both histopathology and clinical follow-up as reference standards (20,22,23,25,27,(29)(30); three studies used only clinical follow-up evidence as the reference standard (24,27,28); one study used only clinical follow-up evidence as the reference standard (21). Of all 11 studies, five studies (23,(26)(27)(28)30) enrolled patients prospectively.…”

“…Five studies enrolled patients in a consecutive manner (20,23,27,29,30). For total scan time including patient positioning, six studies (20)(21)(22)(23)(24)28) were within 55 minutes, one study (27) was 75.8 minutes, and the others were not documented.…”

Risonanza magnetica whole-body per l’identificazione delle metastasi scheletriche: confronto con la scintigrafia ossea

“…Technical improvements concerning new sequences and faster methods for localising the signal have made it possible to use MRI as a rapid imaging tool for whole-body surveys and thus to screen patients for bone metastases. The WB-MRI technique can, however, be used for detecting a variety of pathological conditions [26]. WB-MRI may allow simultaneous evaluation of soft tissues and organs, giving an overview of total tumour burden in affected patients [10].…”

Fortschritte in der Diagnostik anorektaler Erkrankungen

“…Eine ganze Reihe von Untersuchungen konnten die Vorteile dieses Verfahren bestätigen, lassen jedoch zeitliche und ökonomische Aspekte nahezu unberücksichtigt [16,40].…”