Why Do People Delay Accessing Health Care for Knee Osteoarthritis? Exploring Beliefs of Health Professionals and Lay People

Prasanna, Shreya S.; Korner‐Bitensky, Nicol; Ahmed, Sara

doi:10.3138/ptc.2011-50

Cited by 39 publications

(40 citation statements)

References 16 publications

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“…However, many people experience significant challenges accessing physical therapy services , including difficulties obtaining referrals or appointments, long waiting times , and limited availability of care in some regional or remote areas . People with knee OA who have difficulties accessing appropriate health care often delay seeking care , possibly to the detriment of their symptoms. New models of physical therapy service delivery that are accessible to the wider population are needed.…”

Section: Introductionmentioning

confidence: 99%

Physical Therapists’ Perceptions of Telephone‐ and Internet Video–Mediated Service Models for Exercise Management of People With Osteoarthritis

Lawford

Bennell

Kasza

et al. 2017

Arthritis Care & Research

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Physical therapists agree that telerehabilitation offers time-saving and privacy advantages for people with osteoarthritis and perceive video-delivered care more favorably than telephone-delivered services. However, most do not like the lack of physical contact with either service model. These findings may inform the implementation of telerehabilitation osteoarthritis services and the training needs of clinicians involved in delivering care.

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Section: Introductionmentioning

confidence: 99%

Physical Therapists’ Perceptions of Telephone‐ and Internet Video–Mediated Service Models for Exercise Management of People With Osteoarthritis

Lawford

Bennell

Kasza

et al. 2017

Arthritis Care & Research

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“…Knee osteoarthritis (KOA) causes the most severe economic and psychological burdens because pains in weight-bearing joints often need surgical intervention [ 2 ]. Although the etiology of KOA remains unclear, previous evidence show aging, obesity, history of injury, and smoking habit are all associated with risks of KOA [ 3 ]. Notably, genetic factors account for 50% of the risk of OA development [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Association between TLR-9 gene rs187084 polymorphism and knee osteoarthritis in a Chinese population

et al. 2017

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Osteoarthritis (OA) is a complex disease that is induced by many genetic risk variants and other factors. To examine the role of toll-like receptor 9 (TLR-9) in OA patients, we conducted a case–control study involving 215 knee OA (KOA) patients and 215 controls in a Chinese population. Genotyping with a custom-by-design 48-Plex single nucleotide polymorphism Scan™ Kit showed the TLR-9 gene rs187084 polymorphism was associated with an increased risk of KOA. Stratification analyses further validated this finding among old people (age ≥ 55 years). In conclusion, TLR-9 gene rs187084 polymorphism is positively correlated with susceptibility to KOA, especially among old people. Nevertheless, this finding should be confirmed by larger size studies with more ethnic populations.

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“…OA is a multistep, multifactorial disease that involves a complex interplay between genetic and environmental factors. Besides the traditional common risk factors, such as aging, obesity, previous injury, smoking habit and hormone therapy [ 2 ], recent studies have revealed that inflammatory processes play a pivotal role in OA pathogenesis [ 3 ]. Proinflammatory cytokines are now implicated as important mediators in OA, and TNF-α and interleukin 1 beta (IL-1β) are considered the major factors.…”

Section: Introductionmentioning

confidence: 99%

Meta-analysis of tumor necrosis factor alpha -308 polymorphism and knee osteoarthritis risk

Kou

2014

BMC Musculoskelet Disord

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BackgroundSeveral case–control studies have been conducted to clarify the association between the tumor necrosis factor alpha (TNF-α) -G308A polymorphism and risk of osteoarthritis (OA); however, the results are inconsistent. This meta-analysis was performed to clarify this issue using all the available evidence.MethodsEligible articles were retrieved by searching PubMed, Web of science and Google scholar. The strength of the association between the TNF-α -G308A polymorphism and risk of OA was assessed by odds ratios (ORs) with the corresponding 95% confidence interval (CI) for each study.ResultsSeven studies were included in the meta-analysis, which included 983 OA cases and 1355 controls. The pooled analysis based on all included studies showed a significantly increased OA risk in the recessive genetic model analysis (OR = 11.08, 95% CI = 4.75-25.86, p < 0.001) and in the A allele vs. G allele analysis (OR = 2.30, 95% CI = 1.08-4.90). However, there was no statistical difference in the dominant genetic model analysis (OR = 2.45, 95% CI = 0.95-6.27, p = 0.06). Furthermore, we found that OA patients had a higher frequency of the AA genotype (OR = 10.49, 95% CI = 4.47-24.61) and GA genotype (OR = 1.78, 95% CI = 1.03-3.08) compared with the control population.ConclusionOur results suggested that the TNF-α -G308A polymorphism were associated with an increased risk of OA.Electronic supplementary materialThe online version of this article (doi:10.1186/1471-2474-15-373) contains supplementary material, which is available to authorized users.

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Why Do People Delay Accessing Health Care for Knee Osteoarthritis? Exploring Beliefs of Health Professionals and Lay People

Abstract: Participants identified multiple reasons for delays and strategies to counter them. Knowledge about gaps in the OA care process can facilitate physiotherapists' participation in developing strategies for early intervention.

Cited by 39 publications

References 16 publications

Physical Therapists’ Perceptions of Telephone‐ and Internet Video–Mediated Service Models for Exercise Management of People With Osteoarthritis

Physical Therapists’ Perceptions of Telephone‐ and Internet Video–Mediated Service Models for Exercise Management of People With Osteoarthritis

Association between TLR-9 gene rs187084 polymorphism and knee osteoarthritis in a Chinese population

Meta-analysis of tumor necrosis factor alpha -308 polymorphism and knee osteoarthritis risk

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