Polycapillary optics, i.e. shaped arrays consisting of hundreds of thousands of hollow glass capillary tubes, can be used to redirect, collimate or focus X-ray beams. X-rays emitted over a large angular range from conventional laboratory-based sources can be transformed into a beam with a small angular divergence or focused onto a small sample or sample area. Convergent beams of X-rays, with convergence angles as high as 15 , have been produced using polycapillary X-ray optics. Focused-spot sizes as small as 20 mm have been achieved, with¯ux densities two orders of magnitude larger than that produced by pinhole collimation. This results in a comparable decrease in data collection times because of the increase in direct-beam intensity and reciprocal-space coverage. In addition, the optics can be employed to reduce background and provide more convenient alignment geometries. The inverse dependence of the critical angle for total external re¯ection on photon energy results in suppression of high-energy photons. This effect can be employed to allow the use of higher tube potentials to increase the characteristic line emission and has also been employed to increase signi®cantly the K/K ratio in Cu radiation. Measurements of X-ray diffraction data and crystallographic analyses have been performed for systems ranging from elemental crystals to proteins. Data from a lysozyme protein`standard' with a slightly convergent beam, taken in 3 min per frame with 2 oscillation with a 2.8 kW source, re®ned to an intensity variance of 5% compared to a standard data set. High-quality data were also obtained with a 0.03 kW ®xed-anode source and a 2 convergent lens in 5 min per frame.