Wide geographical distribution of internationally rare<i>Campylobacter</i>clones within New Zealand

McTavish, Sharla M.; Pope, Charles E.; Nicol, Carolyn; Sexton, Kevin W.; French, Nigel P.; Carter, P. E.

doi:10.1017/s0950268807009892

Cited by 45 publications

(53 citation statements)

References 28 publications

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“…The highest PSI was observed for genotypes for samples from supplier A and human cases, providing further evidence for the link between this supplier and human cases. This conclusion is supported by the finding that the prevalence of ST-474 was very low in samples from nonpoultry sources in New Zealand (29,34). It is notable that the similarity of supplier A sample genotypes to human sample genotypes is higher than the similarity between poultry supplier sample genotypes.…”

Section: Discussionmentioning

confidence: 69%

“…ST-474 was the genotype most commonly isolated in the winter epidemic in 2006 in New Zealand (29) and along with the other major human STs contributed to the human disease burden throughout the study period (33). To date, this ST has been submitted only once to the Campylobacter PubMLST database (10) (from a chicken sample in the Czech Republic) and has been reported only sporadically (2, 5, 50) outside of New Zealand (29,34,47). This is in contrast to ST-45, which was prevalent in samples from all poultry suppliers and other animal sources tested in the region, both livestock and wildlife, but accounted for far fewer human cases (a total of 8.2%).…”

Section: Discussionmentioning

confidence: 99%

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Molecular Epidemiology ofCampylobacter jejuniin a Geographically Isolated Country with a Uniquely Structured Poultry Industry

Müllner

Collins-Emerson

Midwinter

et al. 2010

Appl Environ Microbiol

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In New Zealand the number of campylobacteriosis notifications increased markedly between 2000 and 2007. Notably, this country's poultry supply is different than that of many developed countries as the fresh and frozen poultry available at retail are exclusively of domestic origin. To examine the possible link between human cases and poultry, a sentinel surveillance site was established to study the molecular epidemiology of Campylobacter jejuni over a 3-year period from 2005 to 2008 using multilocus sequence typing. Studies showed that 60.1 to 81.4% of retail poultry carcasses from the major suppliers were contaminated with C. jejuni. Differences were detected in the probability and level of contamination and the relative frequency of genotypes for individual poultry suppliers and humans. Some carcasses were contaminated with isolates belonging to more than one sequence type (ST), and there was evidence of both ubiquitous and supplier-associated strains, an epidemiological pattern not recognized yet in other countries. The common poultry STs were also common in human clinical cases, providing evidence that poultry is a major contributor to human infection. Both internationally rare genotypes, such as ST-3069 and ST-474, and common genotypes, such as ST-45 and ST-48, were identified in this study. The dominant human sequence type in New Zealand, ST-474, was found almost exclusively in isolates from one poultry supplier, which provided evidence that C. jejuni has a distinctive molecular epidemiology in this country. These results may be due in part to New Zealand's geographical isolation and its uniquely structured poultry industry.

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Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Molecular Epidemiology ofCampylobacter jejuniin a Geographically Isolated Country with a Uniquely Structured Poultry Industry

Müllner

Collins-Emerson

Midwinter

et al. 2010

Appl Environ Microbiol

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show abstract

“…Furthermore, recent studies performed in England, New Zealand, and Scotland have shown that comparison between the sequence types (STs) assigned to human clinical isolates and the STs assigned to environmental and animal isolates allows MLST to be used to assign human isolates to source populations on a probabilistic basis [22][23][24][25][26][27]. Indeed, many of the most prominent multilocus STs, such as STs 42, 45, 48, 61 and 354, isolated from human clinical cases and from animal samples in New Zealand are also among the most commonly observed in other countries [22,24,28]. However, some STs that are prominent in New Zealand are comparatively rare elsewhere including, in particular, ST-474, the most common single ST associated with human clinical campylobacteriosis in New Zealand [22,24,28].…”

Section: Introductionmentioning

confidence: 99%

“…Indeed, many of the most prominent multilocus STs, such as STs 42, 45, 48, 61 and 354, isolated from human clinical cases and from animal samples in New Zealand are also among the most commonly observed in other countries [22,24,28]. However, some STs that are prominent in New Zealand are comparatively rare elsewhere including, in particular, ST-474, the most common single ST associated with human clinical campylobacteriosis in New Zealand [22,24,28]. For example, a sentinel surveillance study conducted from 2005 to 2008 in the Manawatu District of the lower North Island of New Zealand applied source attribution modelling methods to attribute some 70-80% of human campylobacteriosis cases to a poultry source [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Binary genomotyping using lipooligosaccharide biosynthesis genes distinguishes betweenCampylobacter jejuniisolates within poultry-associated multilocus sequence types

Hotter

French

2009

Epidemiol. Infect.

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Campylobacter jejuni is a leading cause of human bacterial gastroenteritis throughout the industrialized world. We investigated whether or not differences in gene complement at the lipooligosaccharide (LOS) biosynthesis locus can identify epidemiologically useful binary genomotypes in 87 C. jejuni isolates from poultry-associated multilocus sequence types (STs) collected during the course of a sentinel surveillance study. Using a PCR-based approach, we correlated assignment of both isolate LOS locus class and binary genomotype with ST. We found that isolates within STs 45, 190, 354 and 474 displayed mosaicism in gene complement at the intra-ST level. For example, based upon their binary genomotypes, we assigned individual ST-45 isolates from human clinical cases as probably originating from either a poultry or wild-bird source. However, intra-ST mosaicism in gene complement was observed alongside broader patterns of congruence in LOS locus class and gene complement that distinguished between isolates from different STs.

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“…Unlike PFGE, MLST has been successfully used in long-term epidemiological studies (27,45) and in deciphering the population structure (2,20,28,45) of Campylobacter on a global scale. MLST has high discriminatory power (23) and standardized nomenclature for STs and clonal complexes (CCs) (3,26).…”

mentioning

confidence: 99%

Decreasing Trend of Overlapping Multilocus Sequence Types between Human and Chicken Campylobacter jejuni Isolates over a Decade in Finland

Haan

Kivistö

Hakkinen

et al. 2010

Appl Environ Microbiol

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We describe the long-term multilocus sequence typing (MLST) analysis of the population structure and dynamics of 454 Finnish human Campylobacter jejuni isolates, as well as 208 chicken isolates, collected during the mid-1990s to 2007. The sequence type clonal complexes (ST CC) ST-45 CC, ST-21 CC, and ST-677 CC were the most common ones found among all isolates, and they covered 73.9% of all isolates. The ST-283 CC also was found frequently among chicken isolates (8.2%). The predominant STs among all isolates were ST-45, ST-50, and ST-677. ST-137 and ST-230 were common among human isolates, and ST-267 was found more frequently among chicken isolates than human isolates. The ST-45 CC was significantly associated with chicken isolates (P < 0.01), whereas the ST-21 CC was associated with human isolates (P < 0.001). The ST-677 CC was not associated with any host (P ‫؍‬ 0.5), and an opposite temporary trend of this complex was seen among chicken and human isolates, with an increase in the former and a decrease in the latter during the study period. Furthermore, the ST-22 and ST-48 CCs were significantly associated with human isolates (P < 0.01), but neither of the CCs was found in chicken isolates. The annual overlap between STs from human and chicken isolates decreased from 76% at the beginning of the study to 58% at the end. Our results suggest that the importance of chicken as a reservoir for strains associated with human infections has declined despite the consumption of domestic chicken meat increasing during the follow-up period by 83%.

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Wide geographical distribution of internationally rareCampylobacterclones within New Zealand

Cited by 45 publications

References 28 publications

Molecular Epidemiology ofCampylobacter jejuniin a Geographically Isolated Country with a Uniquely Structured Poultry Industry

Molecular Epidemiology ofCampylobacter jejuniin a Geographically Isolated Country with a Uniquely Structured Poultry Industry

Binary genomotyping using lipooligosaccharide biosynthesis genes distinguishes betweenCampylobacter jejuniisolates within poultry-associated multilocus sequence types

Decreasing Trend of Overlapping Multilocus Sequence Types between Human and Chicken Campylobacter jejuni Isolates over a Decade in Finland

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