Wild boars: A potential source of <i>Erysipelothrix rhusiopathiae</i> infection in Japan

Shimoji, Yoshihiro; Osaki, Makoto; Ogawa, Yohsuke; Shiraiwa, Kazumasa; Nishikawa, Sayaka; Eguchi, M.; Yamamoto, Takehisa; Tsutsui, Toshiyuki

doi:10.1111/1348-0421.12736

Cited by 11 publications

(16 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 and Table 1). In a recent nationwide survey of the seroprevalence of anti-E. rhusiopathiae antibodies in wild boars, 1,312 of 1,372 wild boars (95.6%) possessed antibodies, including all 16 wild boars (100%) captured in Nagano Prefecture [10,23]. This concurs with our results that wild boars inhabiting Nagano Prefecture are very likely to be exposed to E. rhusiopathiae.…”

Section: E Rhusiopathiaesupporting

confidence: 91%

See 1 more Smart Citation

Serological survey of antibodies to four pathogens in wild boars in Nagano Prefecture, Japan

et al. 2022

View full text Add to dashboard Cite

Wild boars (Sus scrofa) captured or found dead in Nagano Prefecture were surveyed for antibodies to Aujeszky's disease virus (ADV), Erysipelothrix rhusiopathiae, porcine reproductive and respiratory syndrome virus (PRRSV), and Toxoplasma gondii. While all 168 samples tested were negative for anti-ADV antibodies and all 140 samples tested were negative for anti-PRRSV antibodies, all 190 samples tested were positive for anti-E. rhusiopathiae antibodies and 12 of 180 samples were positive for anti-toxoplasma antibodies. These results suggest that since E. rhusiopathiae and T. gondii cause zoonotic diseases, in addition to wild boars being a potential source of infection for domestic pigs, caution should be taken when handling wild boars or eating wild boar meat because of the possibility of human infection.

show abstract

Section: E Rhusiopathiaesupporting

confidence: 91%

“…This concurs with our results that wild boars inhabiting Nagano Prefecture are very likely to be exposed to E. rhusiopathiae. Shimoji et al isolated E. rhusiopathiae from the tonsils of 18 of 20 (90%) wild boars [23], also suggesting that wild boars carry E. rhusiopathiae and are a likely source of infection for domestic pigs.…”

Section: E Rhusiopathiaementioning

confidence: 99%

Serological survey of antibodies to four pathogens in wild boars in Nagano Prefecture, Japan

et al. 2022

View full text Add to dashboard Cite

show abstract

“…strain 2 (serotype 18) [1,2]. E. rhusiopathiae is a small, Gram-positive, slender, straight, rod-shaped bacterium that causes erysipelas in swine and many other animals [3][4][5][6][7][8]. Swine erysipelas can cause pyrexia, lameness, characteristic diamond skin lesions, and even sudden death in growing and adult swine [9].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018

Zhao

et al. 2021

Microorganisms

View full text Add to dashboard Cite

Erysipelothrix rhusiopathiae can cause erysipelas in animals and erysipeloid in humans. Since its recurrence in 2012, swine erysipelas has caused serious losses within the pig industry in China. The aim of this study was to perform multilocus sequence typing and understand the virulence and antimicrobial susceptibility of E. rhusiopathiae isolates in China. Multilocus sequence typing (MLST) of a total of 120 strains was performed, and as a result, three different sequence types were identified, of which ST48 was the main one. Five isolates of each MLST type were randomly selected to be used to challenge mice. ST48 was associated with a higher virulence. Antimicrobial susceptibility was tested using a microdilution technique and, to analyze the resistance mechanism, six strains were selected for genome sequencing. A comparison of the six genomes indicated the presence of a suspected macrolide resistance gene, namely, Erm(A)-like, in erythromycin-resistant strains, which increased the minimum inhibitory concentration (MIC) of erythromycin against E. coli C600 at least four-fold. In addition, three mutations (gyrA86T-I, gyrA90D-N, and parC81S-I) were observed in the quinolone resistance-determining regions (QRDRs) of gyrA and parC in quinolone-resistant strains. After the gyrA gene with the 86T-I mutation or the parC gene with the 81S-I mutation was transfected into E. coli C600, the MIC of enrofloxacin against this strain increased at least two-fold. Our findings provide a theoretical basis for developing antibacterial drugs and may contribute to the clinical prevention and control of E. rhusiopathiae.

show abstract

“…Previously, we confirmed that a serovar 1a mutant with deletion of the whole ERH_1440 gene is as virulent as its parental strain in mice and that virulence was not altered [ 5 ]. However, it is not surprising that E. rhusiopathiae exhibits different pathogenicity between pigs and other hosts [ 10 , 15 ]; thus, it may be interesting to compare the virulence in pigs between the Ishikari strain and its mutant with a 162-bp deletion in ERH_1440.…”

mentioning

confidence: 99%

Genetic analysis of an <i>Erysipelothrix rhusiopathiae</i> swine isolate determined to be serovar 2 by a gel double diffusion test but serovar 1a/2 by a serotyping PCR assay

Shiraiwa

Ogawa

Nishikawa

et al. 2020

The Journal of Veterinary Medical Science

Self Cite

View full text Add to dashboard Cite

We previously developed a multiplex PCR assay for the differentiation of serovar 1a, 1b, 2 and 5 strains of Erysipelothrix rhusiopathiae. In this study, we analyzed the serovar-defining chromosomal region of a serovar 2 swine isolate, which was PCRpositive for both serovars 1a and 2 by the multiplex PCR assay. Genetic analysis of the chromosomal region revealed that, as in serovar 1a strains, the ERH_1440 gene, which is usually truncated or missing in serovar 2 strains, was intact in this strain. This paper first shows an E. rhusiopathiae serovar 2 strain possessing an intact ERH_1440 gene and suggests that care may be needed when determining the serovar of such rare strains by PCR assay.

show abstract

Wild boars: A potential source of Erysipelothrix rhusiopathiae infection in Japan

Cited by 11 publications

References 18 publications

Serological survey of antibodies to four pathogens in wild boars in Nagano Prefecture, Japan

Serological survey of antibodies to four pathogens in wild boars in Nagano Prefecture, Japan

Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018

Genetic analysis of an <i>Erysipelothrix rhusiopathiae</i> swine isolate determined to be serovar 2 by a gel double diffusion test but serovar 1a/2 by a serotyping PCR assay

Contact Info

Product

Resources

About