This paper addresses a study of fault-tolerant control (FTC) for wireless networked control systems (WNCSs) in industrial automatic processes. The WNCSs is composed of many subsystems, which operate with different sampling cycles. In order to meet the real-time requirements and ensure a deterministic data transmission, the time division multiple access (TDMA) mechanism is adopted in WNCSs. The data in WNCSs are transmitted following a TDMA-based scheduler. According to the periodicity, WNCSs integrated with the scheduler is first formulated as discrete linear time periodic systems (LTPSs). Afterwards, a fault estimation method for LTPSs is developed under a H 1 performance specification with a regional pole constraint. With the achieved state observer and fault estimator, an FTC strategy for LTPSs is explored. Finally, the proposed methods are verified on a physical experimental WiNC platform. a wide application of NCSs in industry, it is needed to explore an integrated design of FTC strategies and the networks.Along with the wide application of NCSs in large-scale complex plants, the traditional wired NCSs expose some drawbacks gradually, such as inexpedience of installation and maintenance and increment of cabling costs. Recently, a trend of adopting wireless technology into the traditional wired NCSs, that is, wireless NCSs (WNCSs) [10] has been observed. In order to meet the realtime requirements and ensure a deterministic data transmission, the time division multiple access (TDMA) mechanism is broadly employed in industrial WNCSs. The exchanges of packet-based messages are proceeded after a TDMA-based scheduler, which determines the manner of multiple nodes accessing the network simultaneously. As stated in [11,12], the performance of WNCSs not only depends on the design of control algorithms but also on the scheduling of the shared network resources.The co-design problem of control and scheduling has been an emerging trend in recent years. References [13,14] have addressed this problem for stabilizing a linear time invariant (LTI) system, where only limited nodes had the right to access a shared network. A study of FTC strategy for a kind of NCSs with noise disturbance has been presented in [15], where the NCSs was modeled based on the co-design of information scheduling and control. A predictive control and scheduling has been proposed in [16] to deal with the communication constraints for a set of NCSs with network-induced delays. The conditions for quadratic stabilizability of linear NCSs and communication protocols has been developed in [17]. Moreover, the recent researches have been drawn on the FTC strategies for decentralized industrial processes. For instance, [18] has studied the H 1 FTC problem of largescale NCS with time-varying actuator faults, where the Lyapunov stability theory is used to check the asymptotic stability of the faulty NCS. A quantized control design problem for a class of semi-Markovian jump systems with repeated scalar nonlinearities has been concerned in [19]. Reference [20] h...