There is little doubt that the success and reliability of frac-pack completions in the Gulf of Mexico has become the yard-stick by which Gulf of Mexico sand control completions are currently measured. Simultaneously, StressCage has become common practice as a method to overcome challenges drilling through depleted zones, in order to cope with complex mud-window constraints for new developments and infill wells. The success of these drilling and completion approaches and their rapid widespread application has resulted in ever more depletion. This has potentially created a vicious circle in terms of drilling the well to desired depth vs. the ability to install a low-skin frac-pack completion.While these two techniques in isolation represent uniquely optimal solutions to their individual challenges, there is growing evidence that their application within the same wellbore has the potential to create conflicting ideals. The StressCage application is associated with the plugging of small fractures which have been induced in the wellbore wall, thereby increasing the effective fracture gradient, which allows for the drilling of substantial depletion. However, the presence of a range of widely distributed particle sizes in the mud system, as well as increased general solids loading, may result in deep and invasive plugging of the permeable formations and any smaller fractures within the same open-hole sections. When these plugged formations are then the target for subsequent fracturing operations, there is a significant potential to create near wellbore problems that complicate or bring into question the ability to install a frac-pack completion.This paper will provide a number of examples of the application of StressCage, where resulting frac operations appear to have been hampered or complicated by the use of the StressCage approach and/or associated mud conditions. These examples will provide some evidence of such interactions but, more importantly, demonstrate the contradiction that these two techniques potentially represent. The paper will also outline a scenario resulting from a sand-control lower completion assembly in place, in a new borehole drilled with StressCage method, that could be resistant to any form of frac breakdown (or simple mechanical intervention), and, thereby, compromise the frac and well completion itself.In addition to the case histories, the paper will outline various engineering approaches that should be considered, including geo-mechanical analysis of well placement, identification of near wellbore issues prior to and during the fracturing operations, careful management of stress caged solids makeup, mud management and frac-pack design in order to avoid or overcome such challenges. All of this helps ensure that we do not create the paradox of being able to drill through the undrillable but then creating the unfraccable as a result.