Withania somnifera (L.) Dunal(Pharmacology Activity)

Akram, Muhammad; Mohiuddin, Ejaz; Hannan, Abdul; Usmanghani, Khan

doi:10.1016/s0975-3575(11)80030-1

Cited by 5 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are two tautomeric forms in which curcumin can exist, that are keto and enol. However, in the solution and solid phase, enol appears to be more energetic [11].…”

Section: Phytoconstituents Of Turmericmentioning

confidence: 95%

See 1 more Smart Citation

An Overview of Golden Spice’s (Turmeric) Medicinal Properties for Future Development Potential

Ismail,

Mazuki

2021

MJoSHT

View full text Add to dashboard Cite

Traditional medicines that are derived mainly from herbaceous plants are widely used for years in many regions of the world. Currently, the world is facing the emergence of resistant microorganisms due to the overuse and misuse of antibiotics and the lack of new drug development. In consequence, the discovery of natural phytochemicals that are safe, cheap, non-toxic, and readily available would be an acceptable alternative source. Turmeric, scientifically known as Curcuma longa, in the family of Zingiberaceae (ginger) is well known for its diverse therapeutic properties. The medicinal properties of turmeric include antioxidant, anti-inflammatory, anti-microbial, anti-carcinogenic, cardioprotective, gastroprotective, hepatoprotective, and many more. Numerous studies have shown that curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), which is the most active compound of turmeric, plays a significant role as a therapeutic agent. The present article provides a brief overview of the plethora of research regarding the medicinal properties of golden spice (turmeric), specifically of curcumin's role in the treatment of various illnesses. Interestingly, turmeric might play a role in protecting COVID-19 patients against the development of lung injury caused by cytokine storms. Hence, this warrants further scientific research to monitor the anti-inflammatory effect of turmeric on SARS-CoV-2.

show abstract

“…There are two tautomeric forms in which curcumin can exist, that are keto and enol. However, in the solution and solid phase, enol appears to be more energetic [11].…”

Section: Phytoconstituents Of Turmericmentioning

confidence: 95%

“…The principal compounds of turmeric are called curcuminoids. The main curcuminoids found in turmeric are curcumin, demethoxycurcumin, and bisdemethoxycurcumin [4,11]. Curcumin, which extracted from the ground rhizome Curcuma plant, is a polyphenolic compound.…”

Section: Phytoconstituents Of Turmericmentioning

confidence: 99%

An Overview of Golden Spice’s (Turmeric) Medicinal Properties for Future Development Potential

Ismail,

Mazuki

2021

MJoSHT

View full text Add to dashboard Cite

show abstract

“…Ashwagandha has been used for millennia as a ‘Rasayana’ (rejuvenator) for longevity. It was imported to Europe in the 16th century [ 24 , 25 , 26 ].…”

Section: Specific Nootropic Herb Shrub and Tree Speciesmentioning

confidence: 99%

“…The fruits appear as red berries wrapped in a calyx ( Figure 1 ). The roots are smooth, 1–2 cm in diameter, and 30–40 cm long [ 24 , 27 ].…”

Section: Specific Nootropic Herb Shrub and Tree Speciesmentioning

confidence: 99%

Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers

Malík

Tlustos

2023

Plants

View full text Add to dashboard Cite

Plant-based nootropics are a diverse group of natural drugs that can improve cognitive abilities through various physiological mechanisms, especially in cases where these functions are weakened or impaired. In many cases, the nootropics enhance erythrocyte plasticity and inhibit aggregation, which improves the blood’s rheological properties and increases its flow to the brain. Many of these formulations possess antioxidant activity that protects brain tissue from neurotoxicity and improves the brain’s oxygen supply. They can induce the synthesis of neuronal proteins, nucleic acids, and phospholipids for constructing and repairing neurohormonal membranes. These natural compounds can potentially be present in a great variety of herbs, shrubs, and even some trees and vines. The plant species reviewed here were selected based on the availability of verifiable experimental data and clinical trials investigating potential nootropic effects. Original research articles, relevant animal studies, meta-analyses, systematic reviews, and clinical trials were included in this review. Selected representatives of this heterogeneous group included Bacopa monnieri (L.) Wettst., Centella asiatica (L.) Urban, Eleutherococcus senticosus (Rupr. & Maxim.) Maxim., Ginkgo biloba L., Lepidium meyenii Walp., Panax ginseng C.A. Meyer, Paullinia cupana Kunth, Rhodiola rosea L., Schisandra chinensis (Turcz.) Baill., and Withania somnifera (L.) Dunal. The species are depicted and described, together with their active components and nootropic effects, and evidence of their efficacy is presented. The study provides brief descriptions of the representative species, their occurrence, history, and the chemical composition of the principle medicinal compounds, with uses, indications, experimental treatments, dosages, possible side effects, and contraindications. Most plant nootropics must be taken at optimal doses for extended periods before measurable improvement occurs, but they are generally very well tolerated. Their psychoactive properties are not produced by a single molecule but by a synergistic combination of several compounds. The available data suggest that including extracts from these plants in medicinal products to treat cognitive disorders can have substantial potential therapeutic benefits.

show abstract

“…Ashwagandha has green leaves, branched limbs with seeded yellow lowers. Ashwagandha is an essential herb in Ayurvedic context and also used in a variety of infectious diseases and in lammation conditions (Akram et al, 2011).…”

Section: Botanical Descriptionmentioning

confidence: 99%

Role of Ashwagandha (Withania Somnifera) as Immunomodulator in Coronavirus in a pandemic – A systemic review

Parwe¹,

Nisargandha²,

Morey³

2020

ijrps

View full text Add to dashboard Cite

The novel coronavirus has been transmitted all over the world. Many deaths were occurred due to Coronavirus. The main symptoms are pyrexia, fatigue, and dry cough. Some individual also develops a headache, running nose, congestion, sore throat, shortness of breath. At present, no vaccines or medicines available for the prevention and management of Coronavirus disease. Prevention is better than cure. This verse is famous and all known about it. So now the time has come to used or implement this. Prevention is the only measure to fight against Coronavirus. Ayurveda can offer the best option having preventive as well as curative measures. Many herbs have been mentioned in the Ayurvedic texts, which have immunomodulatory action or works as immunobusting drugs. Ashwagandha is well-known or a far old drug which said in Ayurvedic text as a Rasayan and Immunomodulatory activity. Ashwagandha can be used for the prevention of Coronavirus due to it has property like promoting betterment for health and longevity by an increase defence mechanism. Many kinds of research are conducted on Ashwagandha to prove its immunomodulatory, antioxidant, anti-inflammatory, Neuroprotective. Anti-stress properties. We concluded, in Systemic review to know the role of Ashwagandha in the prevention and curing symptoms of Coronavirus its efficacy and mechanism in Coronavirus. Some more research studies should be on COVID -19 for experimental and clinical validation to needed.

show abstract

Withania somnifera (L.) Dunal(Pharmacology Activity)

Cited by 5 publications

References 6 publications

An Overview of Golden Spice’s (Turmeric) Medicinal Properties for Future Development Potential

An Overview of Golden Spice’s (Turmeric) Medicinal Properties for Future Development Potential

Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers

Role of Ashwagandha (Withania Somnifera) as Immunomodulator in Coronavirus in a pandemic – A systemic review

Contact Info

Product

Resources

About