Background:It is increasingly being realized that many of today's diseases are due to “oxidative stress” that results from an imbalance between formation and neutralization of free radicals. Rasayana Chikitsa is a unique branch of Ayurveda. The word Rasayana means the way for attaining excellent Rasadi Dhatus. Several medicinal plants have been described as Rasayanas in Ayurveda. Ashwagandha and Guduchi are the best among the Rasayanas described by Charaka.Aim:To study the efficacy of Ashwagandha and Guduchi in oxidative stress in healthy volunteers.Materials and Methods:The study was carried out on 30 healthy volunteers after obtaining written informed consent. They were randomly distributed in three groups. Each group was treated with three different colored capsules containing Ashwagandha, Guduchi and placebo in the dose of 1 capsule (500 mg) twice a day for 6 months. The parameters such as hemoglobin%, Erythorcyte Sedimentation Rate (ESR), Malondialdehyde (MDA), Super-Oxide Dismutase (SOD) level, etc., were assessed before and after treatment. The Student's t-test was applied to assess significant variations in all of the studied parameters.Results:In this study, there was a significant increase in SOD level and decrease in MDA level in Ashwagandha and Guduchi groups.Conclusion:Ashwagandha and Guduchi may be helpful in preventing the oxidative stress and premature aging.

Infertility is the major reproductive health problem in today's era. About 15% of couples have infertility problems which 40% are related to the male factors. The oligozoospermia is a condition related to infertility which is associated with low sperm concentration. An objective of this study was to observe the effect of ayurvedic medicine on infertile men and to observe changes in sperm concentration, sperm motility and sperm morphology in the subjects before and after treatment. The interinstitutional study was conducted in the Physiology department, J N Medical College and Panchakarma at Wardha. Patients were also referred from department obstetrics and gynecology, Mahatma Gandhi Ayurved College Hospital and Research Center Salod. All the patients were informed regarding the procedure and the semen sample was collected. It was analyzed as per WHO guidelines. The patients having oligozoospermia were explained about the treatment pattern. They were called again for analysis of semen samples after 3 months and 6 months duration. Oligospermia is the condition in which sperm count <20 Millions/ml. On observation, the results in patients before the treatment showed very less count of the sperm concentration, abnormal morphology and reduced motility was found. After the 3 and 6 months of the treatment percentage of sperm concentration, sperm motility and increased sperm morphology. The treatment of the patients was given oral Ayurvedic medicine in improvement of above said parameters. The conclusion of this study was the Ayurvedic formulation can be used in oligozoospermia patients.

Background: Malavstambha is not mentioned as a disease in any text of Ayurveda, but it is symptoms of many diseases. Many types of diseases caused by ‘Malavstambha’ (sarveshamev kupita malaha). Multiple reasons contribute to this phenomenon, such as the effects of ageing on gut physiology, certain illnesses, medications, reduced mobility, inadequate caloric intake, and anorectal sensory changes. It is a very common problem which is increase day by day. For readily available market preparation is used for malavstambha. There is many formulations are mentioned in Ayurvedic Text but it is not in practice or didn’t researches conduct. Aim: To find out the various formulations for malavstambha.  Result and Observations: In Bhaishajya Ratnawali, Yogratnakar, Charak Samhita, Ashtanga Hriday and Sushruta Samhita,we found many formulations.  Conclusion: There are many formulations mentioned in our Samhitas. Some of them are used in practice, but we have to conduct researches on mentioned formulations and create evidence based protocol for malavstambha.

Background: Obesity (Sthaulya) has been one of the primary diseases of the modern period, with its changing lifestyles, climate, and eating habits. Everyone has become a victim of many diseases caused by poor eating habits, and obesity is just one of them. Obesity is the privilege of the new era of robots and materialistic devices. In 2008, the WHO assessed that 1.5 billion individuals, were overweight and more than 200 million men and almost 300 million women were fat. Objectives: To evaluate the effect of Rodhradigana Vasti in Sthaulya. Study Design: This was an open-labelled single-arm interventional clinical study. Methods: 15 patients of Sthaulya were registered from Panchakarma, and Rodhradigana Vasti was administered for 15 days. Statistical Analysis: The data were statistically analyzed using the Wilcoxon Signed Ranks Test for Subjective Parameter and paired t-test for Objective Parameter. Results: In this study, decreased weight, lipid profile and subjective parameters show positive finding after the intervention of Vasti. Conclusion: Rodhradigana Vasti is one of the best remedies for relieving Sthaulya.

Background: At present, the life style is gradually shifting away from healthy living, and therefore people fall victim of various diseases. Sedentary lifestyle, stress, improper posture, continuous jerky movements, long travelling, etc., put maximum pressure on the spine and lower portion of the pelvis. About 80–90% of people get affected by low back pain and 5% of those become victims of sciatica. Aim: Studying the effect of Trivrut Eranda Tailam and Aragvadha Eranda Tailam Virechana in Gridhrasi (Lumbago sciatica syndrome). Objectives: To study the effect of Trivrut Eranda Tailam in Gridhrasi, To study the effect of Aragvadha Eranda Tailam in Gridhrasi and to compare the effect of Trivrutta Eranda Tailam and Aragavadha Eranda Tailam in Gridhrasi. Methodology: This study will be a Randomized controlled interventional trial to be conducted on 30 participants. The participants will be divided into two groups viz. Group A and Group B. The patient in Group A will be given Trivrutt Eranda Tailam (15 patients) and Group B will be given Aragvadha Eranda Tailam (15 patients). Results: Nitya virechan will be carried out in both these groups. The results will be compared on the basis of SLR test [Straight leg raising test], Lassegue sign, Flip test, Bowstring test and Serum electrolytes used for Gridhrasi. Conclusion: Conclusions will be drawn on the result.