Woodfordia fruticosa: Traditional uses and recent findings

Das, Priya; Goswami, Suchandra; Chinniah, Annalakshmi; Panda, Nilendu; Banerjee, Sukdeb; Sahu, Niranjan P.; Achari, Basudeb

doi:10.1016/j.jep.2006.12.029

Cited by 85 publications

(51 citation statements)

References 60 publications

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“…It is also effective for rheumatism (Paper et al 2005) and uterine disorders (Oudhia 2003). It also has promising antitumor and anti-inflammatory activity (Das et al 2007). (Taylor et al 2002).…”

Section: *Valeriana Jatamansi Jones Valerianaceae; Dku 084mentioning

confidence: 99%

Indigenous Use and Ethnopharmacology of Medicinal Plants in Far-West Nepal

Kunwar

Uprety

Burlakoti

et al. 2009

Ethnobot. Res. App.

346

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Ethnopharmacological knowledge is common and import among tribal populations but much of the information is empirical at best lacking scientific validation. Despite widespread use of plant resources in traditional medicines, bioassay analysis of very few plant species have been conducted to investigate their medicinal properties, and to ascertain safety and efficacy of traditional remedies. The present study analyses indigenous uses of medicinal plants of far-west Nepal and compares with earlier ayurveda studies, phytochemical assessments and pharmacological actions. A field study was carried out in Baitadi and Darchula districts of far-west Nepal. Group discussions, informal meetings, questionnaire surveys and field observations were employed for primary data collection. Voucher specimens were collected with field notes and codes and deposited at Tribhuvan University Central Herbarium (TUCH), Kathmandu. Only 50% of species surveyed shared common uses with ayurvedic medicine. This implies that these herbal remedies are part of an independent health care system in the Nepal Himalaya, which is indigenous and influenced by ayurveda. The folk uses of some of the species were contradicting to those of ayurveda and phytochemical bioassays. A detailed phytochemical study on those species would be an important line of research. IntroductionMedicinal plants help in alleviating human suffering and are widely used for subsistence, home remedies, and trade (Kunwar et al. 2006). It is estimated that 70-80% of people worldwide rely on traditional herbal medicine to meet their primary health care needs (Farnsworth & Soejarto 1991). The ayurveda is an ancient traditional system of medicine with remedies for health and alleviation of illness. The acceptance of the ayurveda is gearing up and use of indigenous drugs of natural/plant origin is a maPublished: January 16, 2009 Ethnobotany Research & Applications 6www.ethnobotanyjournal.org/vol7/i1547-3465-07-005.pdf cuna pruriens (L.) DC. for Parkinson's disease, Commiphora as a hypolipidemic, Asclepias as cardiotonic, psoralens for vitiligo, curcumines for inflammation, baccoside for mental retention, picrosides for hepatoprotective, diosgenin for the synthesis of steroidal hormones, guggulsterons as hypolipidemic, piperidine as bioavailability enhancers, asarone as hallucinogenic, phyllanthins as anti-virals, withanolides and many other steroidal lactones and their glycosides as immunomodulators (Jain 1994, Patwardhan 2000. As an example, the sale of drugs derived from the plant Taxus The increasing use of traditional therapies demands more scientifically sound evidence for the principles behind therapies and for effectiveness of medicines (Patwardhan et al. 2005). The therapies are often criticized due to dearth of research, critical evaluation, in vivo studies and validations (Fong 2002, Houghton 1995 to support the safety of uses. At the same time, ethnopharmacological knowledge is percolating down these days among the tribal population. The present study, therefore aim...

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Section: *Valeriana Jatamansi Jones Valerianaceae; Dku 084mentioning

confidence: 99%

Indigenous Use and Ethnopharmacology of Medicinal Plants in Far-West Nepal

Kunwar

Uprety

Burlakoti

et al. 2009

Ethnobot. Res. App.

346

View full text Add to dashboard Cite

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“…Chemically Oenothein B and woodfordin A, B, and C (Yoshida et al, 1990), Isoschimacoalin-A and five oligomers-woofordin E, F, G, H, I were reported from dried flowers (Kuramochi-Motegi et al, 1992). Quercetin-3-O-(6 -galloyl)-␤-d-galactopyranoside, quercetin-3-O-(6 -galloyl)-␤-d-glucopyranoside, quercetin-3-O-␣-l-arabinoside, quercetin-3-O-oxylopyranoside, myricetin-3-O-6 -O-galloyl)-␤-d-galactopyranoside and myricetin-3-Oarbinopyranoside were isolated from dried flowers and their structures elucidated (Das et al, 2007). Based on its diversified ethnopharmacological/folkloric uses and its use in liver diseases in traditional Indian System of Medicine, present study was conducted to validate the assumption with respect to its hepatoprotective activity using most widely used hepatotoxin CCl 4 in experimental studies.…”

mentioning

confidence: 99%

Hepatoprotective activity of Woodfordia fruticosa Kurz flowers against carbon tetrachloride induced hepatotoxicity

Chandan

Saxena

Shukla

et al. 2008

Journal of Ethnopharmacology

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“…[13][14] Phytochemical studies of Woodfordia fruticosa can be ascribed for its important bioactive phytoconstituents such as flavonoids, sterols, anthraquinones, saponins and tannins. [15][16][17] Earlier studies indicates, that Woodfordia fruticosa possess important pharmacological activities including antipyretic, anti-inflammatory, 18 immunomodulatory, 19 etc. None of herbal origin drug posses combine effect as anti-asthmatic, and anti-tussive activity.…”

Section: Introductionmentioning

confidence: 99%

Phytopharmacological evaluation of aerial parts of Woodfordia fruticosa (L.) Kurz in Cough Variant Asthma

Srivastava¹,

Siddharth²,

Hemant³

et al. 2015

Phcog J

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Background: Cough variant asthma (CVA) is characterized by prolonged non productive cough which responds to bronchodilator therapy. None of herbal drug is reported to possess pharmacological activity against CVA. Objective: To investigate the pharmacological potential of ethanolic extract of Woodfordia fruticosa (L.) Kurz (EEWF) against CVA as well as to develop an efficient screening model for CVA. Material and Method: Anti-tussive effect of EEWF was evaluated against nebulized aqueous solution of 0.1 g/ml of citric acid to determine the cough response. EEWF potential was finally accessed against aerosolic mixture of 0.3 g/ml of citric acid mixed with 0.1% histamine and 2% acetylcholine chloride to evaluate the convulsive latency, percentage protection and cough frequency against CVA. Results: EEWF at aerosolic dose of 6% w/v exhibit decrease in of the average coughs frequency (4.83 ± 0.30) which is quite significant effect as compared to standard drug codeine. EEWF against aerosol induced CVA was found to exhibit a significant bronchoprotection of 41.75% and decreases number of coughs SUMMARY• The present study investigated a potential curative effect of ethanolic extract of Woodfordia fruticosa (L.) Kurz in Aerosol induced Cough Variant Asthma.• As none of any model exists to assess the activity of the drug for CVA, so our study also aimed to develop an effective pharmacological screening model for CVA.• The extract not only protects the animals from bron¬choconstriction and bronchospasm but also suppress the cough frequency, which almost covers the basic etiological relevance for CVA, which pharmacologically corroborates its effective treatment against CVA.

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Woodfordia fruticosa: Traditional uses and recent findings

Cited by 85 publications

References 60 publications

Indigenous Use and Ethnopharmacology of Medicinal Plants in Far-West Nepal

Indigenous Use and Ethnopharmacology of Medicinal Plants in Far-West Nepal

Hepatoprotective activity of Woodfordia fruticosa Kurz flowers against carbon tetrachloride induced hepatotoxicity

Phytopharmacological evaluation of aerial parts of Woodfordia fruticosa (L.) Kurz in Cough Variant Asthma

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