Work of Breathing Dynamics Under Changes of PEEP and Pressure Support in Non-invasive Mechanical Ventilation

Ortega, Yessika María; Muñoz, Isabel Cristina

doi:10.1007/978-3-030-00353-1_36

Cited by 1 publication

(6 citation statements)

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“…This module aims to predict the level of muscular effort of a simulated patient under MV through the controls arranged in the interface. Likewise, the module allows for visualizations of when the subject is exposed to high respiratory work by marking thresholds, according to the literature [4,6,19], so the student can come to a conclusion in this regard.…”

Section: Work Of Breathing Indexes Modulementioning

confidence: 99%

“…Table 2 summarizes the ventilatory mechanics and MV parameters of both tests. The registration protocol, inclusion criteria, and ethical approval are detailed in the work carried out by the GIBIC research group in [4].…”

Section: Work Of Breathing Indexes Module Description Of the Databasementioning

confidence: 99%

“…As the airway resistance increases-represented mainly by the upper airway and the trachea, since they have a smaller cross-sectional area concerning the total area product of the lower branches-the gas flow that crosses the tracheobronchial tree decreases as a consequence of frictional losses [4]. This relationship is observed in Tests A, B, and C of Figure 5(I), so the model has a good response in the maximum flow value after changes in R. The small values on the slopes are due to the low rate of fluid loss.…”

Section: Population Analysismentioning

confidence: 99%

“…The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of University of Antioquia, Approval report 15-59-664. The extra information of Data Base is detailed in [4,20].…”

Section: Institutional Review Board Statementmentioning

confidence: 99%

“…During MV, the effort exerted by respiratory muscles is determined by the patient's ventilatory mechanics and mechanical ventilator settings, which, in spontaneous ventilation, is mainly defined by parameters such as positive pressure at the end of expiration (PEEP) and pressure support (PS). A proper configuration of the mechanical ventilator allows for decreasing the work of breathing and does not generate an unnecessary burden on the patient [4]. Some ventilation indexes have been proposed to assess the effect of MV.…”

Section: Introductionmentioning

confidence: 99%

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Web Applications for Teaching the Respiratory System: Content Validation

et al. 2022

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The subject of respiratory mechanics has complex characteristics, functions, and interactions that can be difficult to understand in training and medical education contexts. As such, education strategies based on computational simulations comprise useful tools, but their application in the medical area requires stricter validation processes. This paper shows a statistical and a Delphi validation for two modules of a web application used for respiratory system learning: (I) “Anatomy and Physiology” and (II) “Work of Breathing Indexes”. For statistical validation, population and individual analyses were made using a database of healthy men to compare experimental and model-predicted data. For both modules, the predicted values followed the trend marked by the experimental data in the population analysis, while in the individual analysis, the predicted errors were 9.54% and 25.38% for maximal tidal volume and airflow, respectively, and 6.55%, 9.33%, and 11.77% for rapid shallow breathing index, work of breathing, and maximal inspiratory pressure, respectively. For the Delphi validation, an average higher than 4 was obtained after health professionals evaluated both modules from 1 to 5. In conclusion, both modules are good tools for respiratory system learning processes. The studied parameters behaved consistently with the expressions that describe ventilatory dynamics and were correlated with experimental data; furthermore, they had great acceptance by specialists.

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Section: Work Of Breathing Indexes Modulementioning

confidence: 99%

Section: Work Of Breathing Indexes Module Description Of the Databasementioning

confidence: 99%

Section: Population Analysismentioning

confidence: 99%

Section: Institutional Review Board Statementmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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