Introducción. Por lo general, la mecánica ventilatoria se ha estimado en modo controlado con el uso de aproximaciones no adecuadas para ventilación espontánea.Objetivo. Medir los cambios de la mecánica ventilatoria ante variaciones de la presión positiva al final de la expiración (PEEP, por su sigla en inglés) y la presión soporte (PS) en ventilación mecánica no invasiva.Materiales y métodos. A través de una estrategia no invasiva, se estimó la mecánica ventilatoria bajo diferentes niveles de PEEP y PS. Para tal fin, se utilizó un simulador mecánico y se registró una base de datos de 14 sujetos sanos conectados de manera no invasiva a un ventilador mecánico.Resultados. Se obtuvieron valores medianos de resistencia y compliancia de 91.2[77.8-135.9]mL/cmH2O y 8.3[6.1-10.4]cmH2O/L/s para los 14 sujetos sanos con PEEP y PS de 0 cmH2O, respectivamente. En los incrementos de PEEP, los sujetos presentaron aumento estadísticamente significativo en la compliancia. Por el contrario, en el incremento de presión soporte, no se observaron cambios de ningún parámetro.Conclusiones. Se encontraron valores de compliancia y resistencia, acordes con los configurados en el simulador mecánico y coherentes con los reportados en la literatura en el caso de sujetos sanos. Esto resulta de gran utilidad al tomar decisiones en unidades de cuidados intensivos.
Introduction
Repeated sports-related concussion has been associated with cognitive deficits, like other forms of traumatic brain injury. Football speed players (FSP; e.g., quarterbacks) are at greater risk of cognitive impairment compared to football non-speed players (FNP). Verbal fluency is typically comprised of two tasks: letter fluency (LF) and semantic fluency (SF). Verbal clustering (production of continuous words belonging to the same category or subcategory) and switching (abandoning an exhausted semantic cluster to a new one in order to produce more words) reflect executive control and strategy use. We examined LF, SF, as well as LF and SF switching and clustering performance in retired FSP, FNP, and healthy comparison (HC) participants.
Methods
The sample consisted of 28 HC, 17 retired FSP, and 53 retired FNP. ANOVAs were conducted to determine group differences on LF, SF, switching, and clustering. FSP and FNP did not differ in concussion frequency.
Results
We found the HC group outperformed the FSP group in LF, p = 0.042, ηp2 = 0.07. For SF, the HC and FNP groups outperformed the FSP group, p = 0.013, ηp2 = 0.09. Furthermore, we found the HC group outperformed both football groups in SF switching, p = 0.000, ηp2 = 0.17.
Conclusion
As expected, the HC group outperformed the FSP group on LF and SF. Also, the FNP group outperformed the FSP group on SF. Interestingly, FSP displayed generally worse performances, supporting the notion that their experience of sub-concussive blows puts them at greater risk for cognitive impairment. Further investigation is needed with larger sample sizes to evaluate SF and other cognitive deficits in the FSP participants.
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