Work with Iodine-125: 8 Years Experience in Brachy-Therapy Sources Production Lab

Souza, Carla Daruich de; Peleias, Fernando S.; Rostelato, Maria E.C.M.; Zeituni, Carlos A.; Tiezzi, Rodrigo; Rodrigues, Bruna T.; Moura, João A.; Costa, Osvaldo Luiz da

doi:10.1007/978-3-319-23024-5_45

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…Souza et al [11] evaluated the risks to which workers are exposed during the production and handling of the 125 I seed sources. Despite the extensive studies mentioned above, little research has been done on the occupational doses received by the eyes and head skin during the 125 I seed implantation procedure.…”

Section: Introductionmentioning

confidence: 99%

Determination of Exposure during Handling of 125I Seed Using Thermoluminescent Dosimeter and Monte Carlo Method Based on Computational Phantom

Poorbaygi,

Salimi,

Torkzadeh

et al. 2023

J Radiat Prot Res

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Background: The thermoluminescent dosimeter (TLD) and Monte Carlo (MC) dosimetry are carried out to determine the occupational dose for personnel in the handling of 125I seed sources.Materials and Methods: TLDs were placed in different layers of the Alderson-Rando phantom in the thyroid, lung and also eyes and skin surface. An 125I seed source was prepared and its activity was measured using a dose calibrator and was placed at two distances of 20 and 50 cm from the Alderson-Rando phantom. In addition, the Monte Carlo N-Particle Extended (MCNPX 2.6.0) code and a computational phantom with a lattice-based geometry were used for organ dose calculations.Results and Discussion: The comparison of TLD and MC results in the thyroid and lung is consistent. Although the relative difference of MC dosimetry to TLD for the eyes was between 4% and 13% and for the skin between 19% and 23%, because of the existence of a higher uncertainty regarding TLD positioning in the eye and skin, these inaccuracies can also be acceptable. The isodose distribution was calculated in the cross-section of the head phantom when the 125I seed was at two distances of 20 and 50 cm and it showed that the greatest dose reduction was observed for the eyes, skin, thyroid, and lungs, respectively. The results of MC dosimetry indicated that for near the head positions (distance of 20 cm) the absorbed dose rates for the eye lens, eye and skin were 78.1±2.3, 59.0±1.8, and 10.7±0.7 µGy/mCi/hr, respectively. Furthermore, we found that a 30 cm displacement for the 125I seed reduced the eye and skin doses by at least 3- and 2-fold, respectively.Conclusion: Using a computational phantom to monitor the dose to the sensitive organs (eye and skin) for personnel involved in the handling of 125I seed sources can be an accurate and inexpensive method.

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Section: Introductionmentioning

confidence: 99%

Determination of Exposure during Handling of 125I Seed Using Thermoluminescent Dosimeter and Monte Carlo Method Based on Computational Phantom

Poorbaygi,

Salimi,

Torkzadeh

et al. 2023

J Radiat Prot Res

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“…A outra modalidade de tratamento, chamada braquiterapia, consiste na introdução de minúsculas fontes contendo material radioativo (sementes) no interior ou próximas do órgão a ser tratado. Atualmente, o isótopo radioativo Iodo-125 é um dos mais usados em braquiterapia prostática [30][31][32][33][34].…”

Section: Formas De Tratamento Do Câncer De Próstataunclassified

Desenvolvimento da metodologia de síntese e purificação dos dímeros L-lactídeo e glicolídeo para produção do poli (ácido lático-co-ácido glicólico) para utilização na produção de fontes radioativas

Júnior¹,

Santos²

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Protocol for reducing radiation exposure during pediatric thoracic radiography

Souza¹,

Freitas

Medeiros

et al. 2022

Journal of Medical Imaging and Radiation Sciences

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Work with Iodine-125: 8 Years Experience in Brachy-Therapy Sources Production Lab

Cited by 4 publications

References 6 publications

Determination of Exposure during Handling of <sup>125</sup>I Seed Using Thermoluminescent Dosimeter and Monte Carlo Method Based on Computational Phantom

Determination of Exposure during Handling of <sup>125</sup>I Seed Using Thermoluminescent Dosimeter and Monte Carlo Method Based on Computational Phantom

Desenvolvimento da metodologia de síntese e purificação dos dímeros L-lactídeo e glicolídeo para produção do poli (ácido lático-co-ácido glicólico) para utilização na produção de fontes radioativas

Protocol for reducing radiation exposure during pediatric thoracic radiography

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