“…These trials are modeled after the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) trial, the first randomized controlled trial (RCT) to show that it is possible to prevent cognitive decline among older at-risk individuals using a multidomain lifestyle intervention (19). With support from the Alzheimer's Association, a Latin American first-of-its-kind study, LatAm-FINGERS, is in the final planning stages and will involve 1,300 subjects from Argentina, Bolivia, Brazil, Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, Mexico, Paraguay, Peru, Puerto Rico, and Uruguay (17,18). The study participants, individuals who are thought to be at a higher risk of cognitive decline due to a range of factors such as sedentary lifestyle, poor diet, and/or a suboptimal metabolic-cardiovascular profile, will be randomly assigned to one of two interventions.…”