Worldwide 10-Year Systematic Review of Treatment Trends in Fibula Free Flap for Mandibular Reconstruction

Okay, Devin; Shetawi, Al Haitham Al; Moubayed, Sami P.; Mourad, Moustafa; Buchbinder, Daniel; Urken, Mark L.

doi:10.1016/j.joms.2016.06.170

Cited by 69 publications

(35 citation statements)

References 18 publications

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“…Okay et al showed that in a recent 10‐year period, there was a surge in publications on the use of fibula free flaps for mandibular reconstruction. A 1.8‐fold increase in the number of publications and a 3.4‐fold increase in the number of operated patients were observed in the second 5‐year period.…”

Section: Discussionmentioning

confidence: 99%

Quality of life after microvascular mandibular reconstruction for osteoradionecrosis—A prospective study

et al. 2019

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Background: Reconstructive surgery for mandibular osteoradionecrosis is increasing; however, evidence regarding the impact on health-related quality of life is lacking. The current exploratory study prospectively investigates whether resection with reconstruction is associated with changes in HRQoL parameters for these patients. Methods: Seventeen patients underwent microvascular reconstruction for mandibular osteoradionecrosis between 2012 and 2015, and 16 completed the EORTC quality of life questionnaires QLQ-C30 and QLQ-H&N35 1 month before and 1 year after surgery. Results: Increases in emotional (P = 0.01) and social functioning (P = 0.004) were observed, together with improvements in the fatigue (P = 0.04), appetite loss (P = 0.02) and pain (P = 0.02) scores, as evaluated by the QLQ-C30. Pain reduction was further confirmed by the QLQ-H&N35 (P = 0.04), which also showed improved scores for feeling ill (P = 0.001) and sexual difficulties (P = 0.04). Conclusion: This exploratory study suggests that microvascular reconstruction after mandibular osteoradionecrosis may improve HRQoL, with an emphasis on pain reduction; however, further studies are needed.

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Section: Discussionmentioning

confidence: 99%

Quality of life after microvascular mandibular reconstruction for osteoradionecrosis—A prospective study

et al. 2019

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“…Mandibular reconstruction after ablative tumour removal is still a challenging task to head and neck surgeons, which aims to achieve the best possible functional and esthetic outcomes. Hidalgo reported the utility of vascularized fibula flaps for mandibular reconstruction in 1989 ( 1 ), Since then, the fibular free flap has become the first option for mandible reconstruction ( 2 , 3 ). This flap has many advantages, including high quality of long bicortical bone grafts, long pedicle, wide vessel, and the ability to incorporate skin and muscle which are required for mandibular reconstruction ( 4 - 6 ).…”

Section: Introductionmentioning

confidence: 99%

Virtual Planning and 3D printing modeling for mandibular reconstruction with fibula free flap

Ren

Gao²,

Li³

et al. 2018

Med Oral

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BackgroundThis study was to evaluate the use of virtual planning and 3D printing modeling in mandibular reconstruction and compare the operation time and surgical outcome of this technique with conventional method.Material and MethodsBetween 2014 and 2017, 15 patients underwent vascularized fibula flap mandibular reconstruction using virtual planning and 3D printing modeling. Titanium plates were pre-bent using the models and cutting guides were used for osteotomies. 15 patients who underwent mandibular reconstruction using fibula flap without aid of virtual planning and 3D printing models were selected as control group. The operation time was recorded and compared in two groups. Accuracy of reconstruction was measured by superimposing the preoperative image onto the postoperative image of mandible. The selected bony landmark, distance and angle were measured.ResultsThe mean total operation time and reconstruction time were 1.60±0.37 and 5.54±0.50 hours in computer-assisted group, respectively; These were 2.58±0.45 and 6.54±0.70 hours in conventional group, respectively. Both operation time and reconstruction time were shorter in computer-assisted group. The difference between the preoperative and postoperative intercondylar distances, intergonial angle distances, anteroposterior distances and gonial angles were 2.92±1.15 and 4.48±1.41mm, 2.93±1.19 and 4.79±1.48mm, 4.31±1.24 and 5.61±1.41mm, 3.85±1.68° and 5.88±2.12° in the computer-assisted and conventional group, respectively. The differences between the preoperative and postoperative mandible is smaller in the computer-assisted group.ConclusionsVirtual planning and 3D printing modeling have the potential to increase mandibular reconstruction accuracy and reduce operation time. we believe that this technology for mandibular reconstruction in selected patients will become a used method and improve the quality of reconstruction. Key words:Mandibular reconstruction, fibula flap, virtual planning, computer-assisted design, 3D printing.

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“…Effective reconstruction or regeneration of the damaged part would be beneficial to patients both physiologically and psychologically (Mao and Prockop, 2012; Mertens et al, 2016). Flap transplants combined with dental implants or obturators are currently the main therapy methods to rehabilitate the defected tissues, however, the functions and esthetics still remain to be improved (Mertens et al, 2016; Okay et al, 2016; Wijbenga et al, 2016). …”

Section: Oral and Maxillofacial Defectsmentioning

confidence: 99%

Application of Stem Cells in Oral Disease Therapy: Progresses and Perspectives

Yang¹,

Qiu²,

Zhou³

et al. 2017

Front. Physiol.

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Stem cells are undifferentiated and pluripotent cells that can differentiate into specialized cells with a more specific function. Stem cell therapies become preferred methods for the treatment of multiple diseases. Oral and maxillofacial defect is one kind of the diseases that could be most possibly cured by stem cell therapies. Here we discussed oral diseases, oral adult stem cells, iPS cells, and the progresses/challenges/perspectives of application of stem cells for oral disease treatment.

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Worldwide 10-Year Systematic Review of Treatment Trends in Fibula Free Flap for Mandibular Reconstruction

Cited by 69 publications

References 18 publications

Quality of life after microvascular mandibular reconstruction for osteoradionecrosis—A prospective study

Quality of life after microvascular mandibular reconstruction for osteoradionecrosis—A prospective study

Virtual Planning and 3D printing modeling for mandibular reconstruction with fibula free flap

Application of Stem Cells in Oral Disease Therapy: Progresses and Perspectives

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