Wound dressings: Current advances and future directions

Abstract

Wound healing is a complicated and continuous process affected by several factors, which needs an appropriate surrounding to achieve accelerated healing. Wound healing process recruits three different phases: inflammation, proliferation, and maturation. Due to the different types of wounds, as well as the advancement in medical technology, various products have been developed to repair different skin lesions. Our objective is to investigate the advancement in wound dressings from traditional to the current methods of treatment. The article presents the characteristics of an ideal wound dressing, the requirements for the appropriate selection of different types of wounds, and a detailed classification of wound dressings. Animal origin, herbal origin, and synthetic dressings are firstly introduced and reviewed. Then, nonmedicated dressings including alginate, hydrogel, and hydrocolloid dressings, as well as medicated dressings are discussed. Finally, the developmental prospectives of the new generations of wound dressings for future researches are presented. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47738.

Multilayered Bio-Based Electrospun Membranes: A Potential Porous Media for Filtration Applications

“…Electrospun nanofibers have attracted substantial attention in numerous applications such as filtration (Bassyouni et al, 2019), tissue engineering (Kouhi et al, 2019), wound dressing (Rezvani Ghomi et al, 2019), encapsulation for drug delivery operation (Ranjbar-Mohammadi et al, 2016), and self-healing (Neisiany et al, 2017), because of their facile and cost-efficient fabrication method and special features (Mohammadzadehmoghadam and Dong, 2019). Electrospinning offers versatile production of fibers with diameters in the order of 10 nanometers to several micrometers from a variety of raw materials (Kumar et al, 2019).…”

Development of Bio-Active Patches Based on Pectin for the Treatment of Ulcers and Wounds Using 3D-Bioprinting Technology

“…There is a vast number of materials available for wound dressing, currently under investigation for different types of wounds and different treatment approaches [1][2][3][4]. The type, depth, and location of a wound, in addition to the extent of damage, the amount of wound exudates and the presence of an infection in the wound site, are key factors in the selection of dressing type.…”

“…The application of traditional dressings, like cotton bandages or gauzes, absorb the moisture contained by the wound, leading to dehydration of the wound surface, and subsequently decreasing the healing rate. Alternative dressings, fabricated by polymers in the form of films, foams or gels, have already been developed and extensively applied for wound management, as they provide the optimum conditions for wound-healing by maintaining the moisture of the wound and at the same time providing a sense of relief to the patient [3,4].To this end, the aim of this study was the development of a wound-dressing system that could provide an adequate moisture environment under occlusive conditions, and the capability to protect the wound from infection and contamination [5], based on natural, non-toxic materials, like pectin, honey, and propolis.…”

Nanocellulose Hybrids with Metal Oxides Nanoparticles for Biomedical Applications

“…The emergence of drug-resistant pathogens is a pressing issue in the biomedical field, especially in wound healing. Multiple studies were conducted towards the development of a novel class of antibacterial materials that meet the mandatory requirements (e.g., biocompatibility, non-toxicity, superior mechanical properties) [ 33 ] and also have a bactericidal action that is not based on antibiotics. One approach consists in the use of a natural polymer which ensures the biocompatibility and serves as a solid support for inorganic NPs together with metal or metal oxides nanoparticles (Au, Ag, ZnO, TiO 2 , CuO) as active antimicrobial fillers [ 34 , 35 , 36 , 37 , 38 , 39 ].…”