Venous leg ulcers are among the most common leg ulcerations. Advancing age, sex, race, phlebitis, family history, obesity, prolonged standing, and number of pregnancies are risk factors. Although the main pathogenetic mechanism is venous hypertension, leading to vein wall damage and thereby a cascade of events resulting in ulceration, there is no consensus about progression from venous hypertension to ulceration.Diagnosis is based on a thorough patient history and physical examination. A typical venous ulcer is shallow and has irregular, well-defined borders with surrounding skin alterations. However, variable vascular and laboratory tests and skin biopsy may occasionally be necessary in differential diagnosis.Although pain reduction, closure of the ulcers, and prevention of the recurrences are the main goals of the treatment, targeted therapy should be the reversal of deep venous insufficiency. Leg elevation and long-term compression therapy are essential in this context. Additionally, appropriate wound care including infection control, debridement, dressings, and antibiotics should be performed and, if needed, adjuvant therapies should be planned according to the patient.