Wound Healing and Clinical Impact of Primary Suture in Surgery of Tumors of Soft Tissue of the Head and Neck

Abstract

Analyzed the results of treatment of 584 patients operated on for soft tissue tumors of the head and neck with the elimination of the defect formed by directly comparing the edges of wounds by primary suture. Taking into account the level of the wound by M.I. Kuzin et al. (1977), the dynamics of clinical and laboratory results, morphological, biological research, local thermometry and vulnotenziometry. Statistical significance was estimated using the Student's t-test, Mann–Whitney U-test, and criteria χ2 and Fisher with certainty changes in p < 0.05. Found that in the majority of patients kept the wound heals biologically programmed tissue reactions. At the same time, high bacterial contamination of integumentary tissues in the area of operations, especially against the background of the malignant tumor was a risk factor for the development of wound complications in 18 % of patients. The observed the oncological impact was characterized by the five-year survival at 90.6 ± 1.9 %. The 4.5 ± 1.9 % of patients had a direct link to death from malignant tumor.