Wpływ aerodynamiki przepływu powietrza przez nos na fizjologię nosa

Betlejewski, S; Betlejewski, Andrzej

doi:10.1016/s0030-6657(08)70263-4

Cited by 8 publications

(3 citation statements)

References 15 publications

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“…However, some authors point out that in the interpretation of nasal cavity dimensions, especially its width, the mucous membranes covering osseous structures ought to be taken into account. The presence of mucous membrane, of various widths, may contribute to changes in the diameter of the measured ducts [3, 19, 23–28]. …”

Section: Discussionmentioning

confidence: 99%

Nasal Region Dimensions in Children: A CT Study and Clinical Implications

Likus

Bajor

Gruszczyńska

et al. 2014

BioMed Research International

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Atresias of nasal cavity, especially in young children, pose an essential problem in children's otolaryngology. Only a few morphometric studies of nasal cavity concerning healthy neonates and young infants without nasal stenosis are available. Multislice computed tomography is a perfect tool enabling a precise evaluation of anatomic structures. The aim of this study was a complex morphometric evaluation of clinically important bone and mucosal structures of nasal cavity and examination of their dependence on age and sex in children up to 3 years of age. 180 children, age range 0–3 years, were divided into 5 age groups, and measurements of 18 distances between skeletal structures and between mucosal structures of nasal cavity were performed on their CT scans. A correlation between the widths of selected bone structures was examined. There were no statistically significant differences in analyzed morphometric parameters between adjacent age groups. The differences were statistically significant only between extreme age groups. There was a correlation between evaluated structures and age. Our results are a valuable supplement of nasal cavity morphometric data of young children. They may be useful in setting reference values of evaluated parameters in children and in diagnosis and planning of surgical treatment in children's otolaryngology.

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Section: Discussionmentioning

confidence: 99%

Nasal Region Dimensions in Children: A CT Study and Clinical Implications

Likus

Bajor

Gruszczyńska

et al. 2014

BioMed Research International

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“…Veins in the lamina propria form thin-walled cavernous sinusoids, also called cavernous bodies [ 11 ]. Epithelial cells of the nasal respiratory tract play an important role in maintaining an equitable temperature by moisturizing the surface, always keeping it slightly lubricated [ 9 , 10 ], highlighting the importance of moisture regulation in the nasal cavity through water/ion channels like AQPs. Expression of AQPs in the respiratory epithelium of the nasal cavity is summarized in Table 1 .…”

Section: Relationship Between Aqps and The Nasal Respiratory Epithmentioning

confidence: 99%

“…The nose, the primary organ of smell, also functions as part of the body’s respiratory system, providing air for respiration; conditioning the air by filtering, warming, and moistening it; and cleaning itself of foreign debris extracted during inhalation [ 9 , 10 ]. The epithelium of the nasal mucosa is divided into two functional types: respiratory epithelium and olfactory epithelium [ 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Expression, Distribution and Role of Aquaporins in Various Rhinologic Conditions

Jung

Park

Kim

et al. 2020

IJMS

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Aquaporins (AQPs) are water-specific membrane channel proteins that regulate cellular and organismal water homeostasis. The nose, an organ with important respiratory and olfactory functions, is the first organ exposed to external stimuli. Nose-related topics such as allergic rhinitis (AR) and chronic rhinosinusitis (CRS) have been the subject of extensive research. These studies have reported that mechanisms that drive the development of multiple inflammatory diseases that occur in the nose and contribute to the process of olfactory recognition of compounds entering the nasal cavity involve the action of water channels such as AQPs. In this review, we provide a comprehensive overview of the relationship between AQPs and rhinologic conditions, focusing on the current state of knowledge and mechanisms that link AQPs and rhinologic conditions. Key conclusions include the following: (1) Various AQPs are expressed in both nasal mucosa and olfactory mucosa; (2) the expression of AQPs in these tissues is different in inflammatory diseases such as AR or CRS, as compared with that in normal tissues; (3) the expression of AQPs in CRS differs depending on the presence or absence of nasal polyps; and (4) the expression of AQPs in tissues associated with olfaction is different from that in the respiratory epithelium.

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Computational model of particle deposition in the nasal cavity under steady and dynamic flow

Karakosta

Alexopoulos

Kiparissides

2013

Computer Methods in Biomechanics and Biomedical Engineering

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A computational model for flow and particle deposition in a three-dimensional representation of the human nasal cavity is developed. Simulations of steady state and dynamic airflow during inhalation are performed at flow rates of 9-60 l/min. Depositions for particles of size 0.5-20 μm are determined and compared with experimental and simulation results from the literature in terms of deposition efficiencies. The nasal model is validated by comparison with experimental and simulation results from the literature for particle deposition under steady-state flow. The distribution of deposited particles in the nasal cavity is presented in terms of an axial deposition distribution as well as a bivariate axial deposition and particle size distribution. Simulations of dynamic airflow and particle deposition during an inhalation cycle are performed for different nasal cavity outlet pressure variations and different particle injections. The total particle deposition efficiency under dynamic flow is found to depend strongly on the dynamics of airflow as well as the type of particle injection.

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Wpływ aerodynamiki przepływu powietrza przez nos na fizjologię nosa

Cited by 8 publications

References 15 publications

Nasal Region Dimensions in Children: A CT Study and Clinical Implications

Nasal Region Dimensions in Children: A CT Study and Clinical Implications

Expression, Distribution and Role of Aquaporins in Various Rhinologic Conditions

Computational model of particle deposition in the nasal cavity under steady and dynamic flow

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