A horizontal printed Write-Once-Read-Many (WORM) resistive memory has been developed for use in wireless sensor tags targeting single-event detection in smart packaging applications. The WORM memory can be programmed using a 1.5-V printed battery. An alternative programming method is to use chemical sintering which allows the development of exposure-time triggered single event tags that can be accessed wirelessly. The new WORM memory has very low losses in the ON-state which allows direct integration into antenna structures. A sensor tag that utilizes the WORM memory functionality and the well established Electronic Article Surveillance (EAS) communication standard has been outlined. Both active and fully passive sensor tag solutions have been proposed. The role of printed electronics in smart packaging applications has been reviewed and discussed. Important enabling factors for the future development have been highlighted, such as the need for hierarchical design and test tools, better printed interconnect technologies as well as better components that allow communication with existing information and communication technology (ICT) standards. This is illustrated and underlined by the presented smart packaging concept demonstrators.