Xanthelasma Palpebrarum Treatment with a 1,450-nm-Diode Laser

Abstract

The 1,450-nm-diode laser treatment is a new, valuable treatment option for xanthelasma palpebrarum, offering relatively mild side effects. Studies including long term follow up and a comparison with alternative treatment modalities are necessary to further assess the clinical utility of this treatment. The authors have indicated no significant interest with commercial supporters.

Treatment of Xanthelasma Palpebrarum by the Pinhole Method Using a 10,600-nm Carbon Dioxide Laser

“…Nonablative laser devices have been reported to be effective in the treatment of XP lesions. 5,6 Previously, Park et al 6 demonstrated the use of a 1,450-nm diode laser as a new, effective, and safe therapeutic option for XP. In their report, a 1,450-nm diode laser was effectively used to destroy sebaceous glands by administering a photothermal zone to the dermis at a depth of 100-500 μm.…”

“…In their report, a 1,450-nm diode laser was effectively used to destroy sebaceous glands by administering a photothermal zone to the dermis at a depth of 100-500 μm. 6 However, the penetration depths of individual laser devices are limited according to their device-specific wavelengths, and repetitive treatments are frequently required. 2 Moreover, because nonablative laser devices are not widely used in many clinics, the cost-effectiveness of new laser devices for treatment of XP remains to be evaluated.…”

“…1 To date, several studies have reported on the therapeutic efficacies of ablative and nonablative lasers for XP, including 10,600-nm carbon dioxide (CO2) lasers, erbium-doped yttrium aluminum garnet (YAG) lasers, 1,550-nm erbium-doped fractional lasers, pulsed dye lasers, Q-switched neodymium (Nd):YAG lasers, and 1,450-nm diode lasers. [2][3][4][5][6] The pinhole method using a CO2 laser refers to a procedure in which multiple small holes mimicking sweat pores are made on skin lesions, such as burn scars and syringomas. 7,8 Puncturing the targeted skin lesions with the pinhole method is easy to perform and results in less oozing and post-therapy erythema.…”

Successful Cosmetic Ablation of Xanthelasma Palpebrarum With Low-Voltage Radiofrequency

“…Considered a cutaneous indicator of dyslipidemia, 25% to 70% patients may be normolipidemic. 1 Many treatments are in vogue: surgical resection, trichloroacetic acid (TCA), cryotherapy, and various lasers. [1][2][3][4] Radiofrequency (RF) ablation, a time-tested modality omnipresent in a dermatosurgical unit also gives excellent results.…”

“…1 Many treatments are in vogue: surgical resection, trichloroacetic acid (TCA), cryotherapy, and various lasers. [1][2][3][4] Radiofrequency (RF) ablation, a time-tested modality omnipresent in a dermatosurgical unit also gives excellent results. 5 A 55-year-old woman of skin Type IV presented with multiple periocular yellowish plaques of size 0.5 · 0.5 cm to 2 · 2.5 cm (Figure 1).…”