Xanthic Variant of Non‐ossifying Fibroma (So‐called Xanthofibroma) of the Mandible

Ide, Fumio; Kusuhara, Shinji; Onuma, Heiji; Miyake, Tateo; Umemura, Shin‐ichiro

doi:10.1111/j.1440-1827.1982.tb02034.x

Cited by 8 publications

(6 citation statements)

References 13 publications

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“…The radiographic appearance as a well-demarcated multilocular radiolucency with sclerotic borders in the current case and in the majority of other cases reported in the mandible [16,18,19,21] is similar to the typical radiographic appearance in the long bones [7,20].…”

Section: Discussionmentioning

confidence: 57%

The Non-ossifying Fibroma: A Case Report and Review of the Literature

Bowers

Cohen

Bhattacharyya

et al. 2012

Head and Neck Pathol

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The non-ossifying fibroma (NOF) is a benign, non-neoplastic lesion most commonly seen in the metaphyses of the long bones in children. While rare, the NOF has been reported in the mandible. The NOF in the extra-gnathic skeleton has a characteristic radiographic appearance, is typically asymptomatic and has a variable histologic make-up. Correlation of the radiographic appearance, clinical presentation and histopathology allows for differentiation of the NOF from odontogenic and nonodontogenic cysts and tumors. We report a new case of this interesting entity and review the radiographic, clinical and histologic features of the gnathic NOF reported in the literature. A thorough search of the English language literature returned a total of 19 cases of NOF involving the gnathic bones.

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Section: Discussionmentioning

confidence: 57%

The Non-ossifying Fibroma: A Case Report and Review of the Literature

Bowers

Cohen

Bhattacharyya

et al. 2012

Head and Neck Pathol

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“…Although the pool of cases is small, the most common presentation of mandibular NOFs can be estimated from a review of the literature (Table 1). Including the current report, 24 cases were identified 2,5–24 . Roughly 67% of cases were seen in females, with an average age at presentation of approximately 19 years old.…”

Section: Discussionmentioning

confidence: 80%

“…Including the current report, 24 cases were identified. 2,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] Roughly 67% of cases were seen in females, with an average age at presentation of approximately 19 years old. This drastically differs from the NOFs of the long bones, which are twice as common in males as they are in females, 25 with a mean age of just 12 years old.…”

Section: Discussionmentioning

confidence: 99%

Non‐ossifying fibroma of the mandible: A case report and review of the literature

Clark,

Brierley,

Chan

et al. 2023

Oral Surgery

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The case reported here is a large non‐ossifying fibroma (NOF) of the mandible presenting in a 24‐year‐old male patient. The lesion was diagnosed through radiological and histopathological assessment. It remains under observation without surgical intervention, despite its large size, as the extensive surgery to remove it is not currently justifiable. Whilst common at the metaphysis of the long bones in paediatric patients, NOFs are rarely observed in the jaw bones. These benign fibrous lesions are often asymptomatic and may be an incidental radiological finding. Most NOFs of the limbs presenting in children will not require any treatment, and spontaneously resolve when growth ceases. However, regarding mandibular lesions, the majority of historical cases have been successfully treated with curettage and do not recur. Due to their scarcity, the outcomes for untreated NOFs of the gnathic bones are not reliably known. We discuss the clinical, radiological and histopathological findings for this case. A thorough literature review of previous reports of this rare entity reveals the typical characteristics and behaviour of this lesion.

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“…Our review of the literature found only 14 previously reported cases of nonossifying fibroma involving the jawbones. [2][3][4][5][6][7][8][9][10][11][12][13][14] In the 14 earlier cases, the mass was located in the posterior part of the mandible, where it often involved the condyle, ramus, and coronoid process. There was a marked female preponderance (female-to-male ratio: 11:3), and the mean age at diagnosis was 19.64 years (range: 6 to 49).…”

Section: Discussionmentioning

confidence: 99%

“…Its occurrence in the jawbone is very rare; to the best of our knowledge, only 14 cases of nonossifying fibroma of the mandible have been previously reported in the literature. [2][3][4][5][6][7][8][9][10][11][12][13][14] In this article, we describe a new case and review the relevant literature on this topic.…”

Section: Introductionmentioning

confidence: 99%

Nonossifying Fibroma (Metaphyseal Fibrous Defect) of the Mandible in a 15-Year-Old Boy

et al. 2015

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We describe a rare case of nonossifying fibroma of the mandible in a 15-year-old boy who presented with a left mandibular swelling. Conventional imaging showed an expansile radiolucent lesion involving the angle and the body of the left mandible. The lesion was curetted, and a miniplate was implanted at the excision site. Microscopic examination of the removed specimen revealed a cellular lesion characterized by a proliferation of uniform spindleshaped cells in a vague but prominent storiform pattern, which represented the classic appearance of nonossifying fibroma. Three months later, radiography detected a fracture of the implantation plate. The area was re-explored with curettage of the soft tissue, which on microscopy demonstrated findings similar to the initial curettage findings. Follow-up radiology revealed satisfactory healing of the jaw, and no further recurrence was seen 2 years after the initial surgery. We present this case to highlight the importance of recognizing nonossifying fibroma in the mandible, which can be easily confused with more common mandibular lesions.

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Xanthic Variant of Non‐ossifying Fibroma (So‐called Xanthofibroma) of the Mandible

Cited by 8 publications

References 13 publications

The Non-ossifying Fibroma: A Case Report and Review of the Literature

The Non-ossifying Fibroma: A Case Report and Review of the Literature

Non‐ossifying fibroma of the mandible: A case report and review of the literature

Nonossifying Fibroma (Metaphyseal Fibrous Defect) of the Mandible in a 15-Year-Old Boy

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