Yabani Zehirli Mantar Entoloma sinuatum (Bull.) P. Kumm 'un (Boletales) Biyolojik Aktiviteleri

Abstract

In many studies conducted in recent years, it has been found that the beneficial natural ingredients found in mushrooms are very important in curing various diseases and eliminating disease factors. It has been reported that fungi that spread in different countries have biological activities. In this study, antioxidant level (TAS), oxidant level (TOS), and antibacterial and antifungalactivity of Entoloma sinuatum (Bull.) P. Kumm were determined. Ethanol extract of the mushroom was extracted in a Soxhlet apparatus. Antioxidant and oxidant levels were determined using Rel Assay TAS and TOS kits. Also, antimicrobial activity was tested against bacterial and fungal strains using the agar dilution method. As a result of the studies, the TAS value of the mushroom was determined 2.64±0.15, the TOS value was 6.58±0.23, and the OSI (Oxidative stress index) value was 0.25±0.02. In addition, it was determined that the ethanol extract of the mushroom was effective against bacteria at 200 and 400 μg/mL, and against fungi at 50 μg/mL concentrations. As a result, it was determined that E. sinuatum is a natural antioxidant and antimicrobial agent.

Medicinal mushrooms: a comprehensive study on their antiviral potential

“…Furthermore, these properties have extensive medicinal applications. Numerous studies have documented the diverse biological activities of mushrooms, including but not limited to antioxidant, anticancer, antimicrobial, antiviral, DNA protective, antiproliferative, antiinflammatory, and hepatoprotective properties [9][10][11][12][13][14][15][16][17][18]. The assessment of the biological properties of fungi holds significant importance in the medical domain.…”

Isolation and structure elucidation of bioactive metabolites from poroid fungi of Hymenochaetaceae and Meripilaceae

“…45 In addition, the following compounds were isolated from the species: pomacerone (furanoid triterpene), ursolic acid, javeroic acid, phellinic acid, senexdiolic acid 46 , albertic acid, natalitic acid, torulosic acid (triterpene acids), ergosta-7,22-dien-3β-ol, and ergosterol peroxide. 45,47 Former studies also determined the total carbohydrate and protein levels, the monosaccharide composition in the polysaccharide extract of the mushroom, 48 the phenolic acid composition 44,49 (gallic acid, catechin, chlorogenic acid, syringic acid and benzoic acid), 49 the average amount of heavy metals (Cd, Cr, Cu, Mn, Zn), 50 boron 51 and trace elements (Na, Mg, Al, P, S, K, Ca, Cl, Fe, V, Cr, Co, Ni, Cu, Zn, Cs, Ba, Ce, Pb, Th, U). 31 The polysaccharides in the mushroom demonstrated remarkable biological activity in different antioxidant assays, including DPPH, ABTS, CUPRAC and metal chelating assay.…”

“…48 Additionally, the antioxidant property of the ethanolic extract was examined by DPPH assay and measuring total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI), meanwhile the fungal sample demonstrated weak cytotoxic effect on A549 cells. 49 Furthermore, the potential cytotoxicity on MCF-7 (breast cancer), PC-3 (prostate cancer), and 3T3…”