Yaşlı yetişkinlerde sarkopeni prevalansı ve yaşam kalitesi: Türkiye’nin doğusundan bir araştırma

Abstract

Aim: Sarcopenia as a geriatric syndrome decreases quality of life and increases functional dependency, hospitalization and mortality. The aim of this study is to investigate the prevalence of sarcopenia among community-dwelling people aged 65 years and older in Muş province and to examine its effects on quality of life. Materials and Methods: In this study we have interviewed 371 community-dwelling older adults. A total of 186 older adults from the rural area and 185 older adults from Muş city center were enrolled in the study. Data was collected through face-to-face interviews conducted in the participants' homes by trained researchers. The presence of sarcopenia, socio-demographic characteristics (place of residence, gender, age), presence of chronic diseases, polypharmacy, body mass index, and quality of life with Short Form-36 were determined. Muscle mass, handgrip strength and gait speed were determined for defining sarcopenia. Results: The mean age of participants was 72.3 ± 6.8 years (65-100) and 46.1% of them were females. The prevalence of sarcopenia was 11.8% among older people residing in the rural area whereas the prevalence was 21.6% among older individuals living in the city center (p = 0.012). Sarcopenic patients were older, more underweight, hypertensive, and had lower calf circumference, gait speed, and grip strength in males than non-sarcopenic patients (p <0.0001, p <0.0001, p = 0.005, p <0.0001, p = 0.001, p <0.0001, respectively). There were important distinction between sarcopenic individuals and non-sarcopenic individuals in terms of physical function, physical role weakness and emotional role weakness (p = 0.021, p = 0.006 and p = 0.009, respectively). Conclusion: Sarcopenia is very common among older adults, especially in the city center, and the presence of sarcopenia has detrimental effects on the quality of life.

The prevalence and impact of sarcopenia in myeloproliferative neoplasms

“…In hospitalized patients the prevalence is 14.7%, in nursing home residents the prevalence is 59%, in community residents the prevalence ranges from 12.9-40.4%, and in cancer patients the prevalence is 38.6% [13]. The prevalence of sarcopenia was found to be 11.8% among elderly Turkish individuals living in rural areas; it was 21.6% in among Turkish individuals living in urban areas [14]. A meta-analysis of 1578 patients with different hematological malignancies revealed that 39.1% of patients with lower overall survival were sarcopenic [15].…”

“…Sarcopenia is a common disease worldwide, and it is especially prevalent in elderly populations [11,14]. It is also associated with sex, disease status and comorbidities, and the type and duration of treatment (e.g., high-dose chemotherapy and steroids) [17].…”

Performance Evaluation of Machine Learning Algorithms for Sarcopenia Diagnosis in Older Adults

“…Values at a 95% confidence level, 5% margin of error, and 11.8% of the population proportion were used for calculations, with a sample size of a minimum of 160 participants needed for this study. Considering the losses-by taking 20% more participants-210 participants were included in this study [35].…”

The Effect of Knee Brace on Knee Joint Proprioception and Static Balance in Sarcopenic Elderly Patients with Knee Osteoarthritis

“…Örneklem büyüklüğü (Epi Info TM Hastalık Kontrol ve Önleme Merkezi, Atlanta, Georgia, ABD) programında, 86.539 toplam 65 yaş üzeri nüfus üzerinden, diz osteoartrit prevalansı %24,8, sarkopeni prevalansı %16,7 olmak üzere %5 hata payı ve %95 güven aralığıyla hesaplandı. [20][21][22] Alt ekstremite cerrahisi geçirenler, son 6 ay içinde intraartiküler girişim yapılanlar, inflamatuar romatolojik hastalığı bulunanlar, santral veya periferik sinir sistemini etkileyebilen inme, nörodejeneratif hastalıklar, polinöropati, multipl skleroz gibi hastalığı olanlar, kognitif disfonksiyonu olanlar, denge ve propriyoseptif duyuyu etkileyebilen diabetes mellitus, tiroid fonksiyon bozuklukları, B12 vitamin yetersizliği, kronik böbrek yetersizliği gibi endokrin, metabolik veya sistemik hastalığı olanlar, sandalyeden kalkma testini yapamayacak kadar şiddetli sarkopenisi olanlar, fizik muayenede bağ laksitesi veya eklem hareket açıklığında kısıtlılık tespit edilenler araştırmaya dâhil edilmedi. Araştırma öncesi, araştırma protokolü Sivas Cumhuriyet Üniversitesi Girişimsel Olmayan Klinik Araştırmalar Etik Kurulu tarafından onaylandı (tarih: 20 Aralık 2020, no: 2020-12/11), katılımcıların yazılı ve sözlü onamları alındı, araştırma süresince Helsinki Bildirgesi ve İyi Klinik Uygulamalar Kılavuzu kurallarına uyuldu.…”