Year in review in Intensive Care Medicine 2013: I. Acute kidney injury, ultrasound, hemodynamics, cardiac arrest, transfusion, neurocritical care, and nutrition

Early fluid accumulation in children with shock and ICU mortality: a matched case–control study

“…However, once fluid overload sets in, mortality remains high, irrespective of the intervention strategy [8,27,28], suggesting that it is the prevention of fluid overload which may be essential to improved outcomes. Fluid resuscitation at the time of ICU admission is a potential source of excessive fluid administration that may lead to overload.…”

Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients

“…Cox regression analyses revealed that higher Acute Physiology and Chronic Health Evaluation (APACHE) II scores and less negative GLSs were independent predictors of ICU and hospital mortalities. GLS was found Introduction Despite recent significant therapeutic advances, the mortality rate of critically ill patients with sepsis remains high [1][2][3]. Many septic patients admitted to the intensive care unit (ICU) do not exhibit any clinical signs or symptoms of myocardial injury, but up to 85 % of septic patients have cardiac involvement, associated with hospital mortality [4].…”

Use of infusion solutions in critically ill: Literature review

“…Primena HES-a 130/0,4 nije dovela do oštećenja bubrežne funkcije, kao ni do poremećaja koagulacije. Nasuprot tome, pojava brojnih studija koje su ispitivale koja vrsta rastvora ima prednost kod septičnih pacijenata, pokazala je da HES narušava bubrežnu funkciju 39,40 , funkciju jetre 41 , izaziva svrab kože 41 . Jedno od objašnjenja tih pojava je da se HES dugotrajno akumulira u tkivima 42 .…”