1953
DOI: 10.1021/jf60001a016
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Yeast, A Source of Biochemical Intermediates

Abstract: Modern medical science has focused attention on the chemistry of living cells. This report describes methods for recovering from yeast, compounds essential to all living tissue. Nucleic acid is readily extracted from yeast in yields of 6% on a dry basis. From it, nucleotides and nucleosides are prepared by hydrolysis. Yeast enzyme systems are used to convert nucleosides to phosphorylated esters, and to prepare sugar phosphates. This organism is also a good source for glutathione and cozymase. The yeast derivat… Show more

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Cited by 3 publications
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“…Nucleic acids.-A recent paper by Laufer et al (130) shows that nucleic acid may be extracted from yeast in quantities amounting to 6 per cent of the dry weight. In addition, nucIeotides, nucIeosides, and their products by enzymic conversion, phosphorylated esters and sugar phosphates, as well as glutathione and the components of cozymase are also recoverable in sufficient quantity to render the yeast cell useful as a source of these compounds for investigational or for therapeutic purposes.…”
Section: Other Fungal Substances Of Nutritional Valuementioning
confidence: 99%
“…Nucleic acids.-A recent paper by Laufer et al (130) shows that nucleic acid may be extracted from yeast in quantities amounting to 6 per cent of the dry weight. In addition, nucIeotides, nucIeosides, and their products by enzymic conversion, phosphorylated esters and sugar phosphates, as well as glutathione and the components of cozymase are also recoverable in sufficient quantity to render the yeast cell useful as a source of these compounds for investigational or for therapeutic purposes.…”
Section: Other Fungal Substances Of Nutritional Valuementioning
confidence: 99%