Yersinia enterocolitica in Drinking Water

Schiemann, D. A.

doi:10.1007/978-1-4612-4464-6_15

Cited by 13 publications

(2 citation statements)

References 64 publications

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“…57 Only a few outbreaks of gastrointestinal illness have been reported to be associated with Y. enterocolitica in the environment, in sewage, in surface water with fecal influent, 58,59 and in drinking water. 60,61 …”

Section: Yersinia Enterocoliticamentioning

confidence: 99%

Emerging Waterborne Infections: Contributing Factors, Agents, and Detection Tools

Theron

Cloete

2002

Critical Reviews in Microbiology

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Because microorganisms are easily dispersed, display physiological diversity, and tolerate extreme conditions, they are ubiquitous and may contaminate and grow in water. The presence of waterborne enteric pathogens (bacteria, viruses, and protozoa) in domestic water supplies represents a potentially significant human health risk. Even though major outbreaks of waterborne disease are comparatively rare, there is substantial evidence that human enteric pathogens that are frequently present in domestic water supplies are responsible for low-level incidence of waterborne microbial disease. Although these diseases are rarely debilitating to healthy adults for more than a few hours to a few days, enteric pathogens can cause severe illness, even death, for young children, the elderly, or those with compromised immune systems. As the epidemiology of waterborne diseases is changing, there is a growing global public health concern about new and reemerging infectious diseases that are occurring through a complex interaction of social, economic, evolutionary, and ecological factors. New microbial pathogens have emerged, and some have spread worldwide. Alternative testing strategies for waterborne diseases should significantly improve the ability to detect and control the causative pathogenic agents. In this article, we provide an overview of the current state of knowledge of waterborne microbial pathogens, their detection, and the future of new methods in controlling these infectious agents.

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Section: Yersinia Enterocoliticamentioning

confidence: 99%

Emerging Waterborne Infections: Contributing Factors, Agents, and Detection Tools

Theron

Cloete

2002

Critical Reviews in Microbiology

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“…Yersinia enterocolitica is an enteroinvasive bacterium that causes gastroenteritis in humans. Following oral infection, Y enterocolitica must cross the intestinal epithelium and reach the mucosa in order to produce clinical disease (5,38). The mammalian gastrointestinal tract is lined with a layer of mucus produced by specialized epithelial cells (goblet cells in the small intestine and colon).…”

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Growth in and breakdown of purified rabbit small intestinal mucin by Yersinia enterocolitica

Mantle

Rombough

1993

Infect Immun

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The mucus lining of the gastrointestinal tract serves as a protective barrier over the epithelial surface that must be crossed by invading bacteria seeking entry into the mucosa. The gel-forming component of mucus is mucin, a large polymeric glycoprotein. The present study examined the growth of Yersinia enterocolitica (with and without its virulence plasmid) in purified rabbit small intestinal mucin and the ability of bacteria to degrade mucin. Both vinlent and nonvirulent organisms showed enhanced growth in mucin-supplemented media compared with unsupplemented media, but only at 37°C and not at 25°C. The effects of mucin were not specific because medium supplemented with bovine serum albumin also enhanced bacterial growth at 37rC. Purified mucin was broken down into lower-molecular-weight components (assessed by monitoring its elution profile on a Sepharose CL-2B column) by plasmid-bearing Y. enterocolitica but not by plasmid-cured organisms. Culturing virulent Y. enterocolitica at 25°C completely suppressed its capacity to degrade mucin, suggesting that this activity depends on plasmid expression. These results were confirmed in similar studies with purified rabbit colonic mucin. Mucin-degrading activity could be demonstrated in spent culture media from virulent Y. enterocolitica incubated at 37°C but not in bacterial membrane preparations. Changes in the elution profiles of small intestinal and colonic mucins exposed to plasmid-bearing Y. enterocolitica at 37°C were consistent with proteolytic depolymerization. The ability to grow well in mucin may help Y. enterocolitica to colonize the intestine, while the production of a mucin-degrading enzyme(s) by plasmid-bearing organisms may assist pathogenic strains to solubilize and penetrate the mucus gel layer.

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Source Water Protection: Microbiology of Source Water

Berger

Oshiro

2003

Encyclopedia of Environmental Microbiology

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Pathogen Sources Factors Affecting the Transport of Fecal Pathogens to Surface Water Environmental Factors in Pathogen Survival in Ambient Waters Pathogen Occurrence in Surface Waters Groundwater Indicators of Source Water Quality Nonmicrobial Indicators of Fecal Contamination Laws and Regulations Protecting Drinking Water Sources

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Yersinia enterocolitica in Drinking Water

Cited by 13 publications

References 64 publications

Emerging Waterborne Infections: Contributing Factors, Agents, and Detection Tools

Emerging Waterborne Infections: Contributing Factors, Agents, and Detection Tools

Growth in and breakdown of purified rabbit small intestinal mucin by Yersinia enterocolitica

Source Water Protection: Microbiology of Source Water

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