Yoga for rehabilitation in chronic pancreatitis

Sareen, Surinder; Kumari, V

doi:10.1136/gut.2006.093088

Cited by 19 publications

(6 citation statements)

References 5 publications

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“…This study represents the first known US validation of the ENETS/NANETS guidelines for rectal NETs. Overall, 5-year survival rate was 84.4%, consistent with 88% cited by NET societies and review articles [1,8,11,14,25]. In our study using these criteria, tumor stage and grade accurately predicted clinical outcome and survival, with advanced stage and grade associated with worse outcomes in agreement with the confirmatory European study by Jann et al [23].…”

Section: Discussionsupporting

confidence: 81%

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Clinical and Prognostic Features of Rectal Neuroendocrine Tumors

Weinstock¹,

Ward

Harpaz

et al. 2013

Neuroendocrinology

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Background: Rectal neuroendocrine tumors (NETs) are among the most common NETs. The aim was to validate European Neuroendocrine Tumor Society (ENETS)/North American Neuroendocrine Tumor Society (NANETS) staging and grading systems with regard to clinical outcomes. Methods: A comprehensive database was constructed from existing databases of the Mount Sinai Division of Gastrointestinal Pathology and the Carcinoid Cancer Foundation. Analysis was performed on 141 patients identified with rectal NETs seen at Mount Sinai Hospital between 1972 and 2011. Results: The median age was 52.7 years; 43% were males. Average tumor size was 0.88 cm. NETs <1 cm accounted for 75.6% of the tumors. Stage I, II, III and IV accounted for 79.4, 2.8, 5.0 and 12.8% of the tumors, respectively. G1 tumors accounted for 88.1%, G2 8.3% and G3 3.6%. Of G1 tumors, 94.6% were stage I and 5.4% were stage IV. The median survival time for all 141 patients was 6.8 years (range, 0.8-34.7 years). The overall 5-year survival rate was 84.4%. The 5-year survival rates for patients in stages I-IV were 92.7, 75.0, 42.9 and 33.2%, respectively. The 5-year survival rates for patients with G1-G3 tumors were 87.7, 47.6 and 33.3%, respectively. Univariate analysis of increased survival showed significance for lower stage, lower grade, smaller size, absence of symptoms and endoscopically treated tumors. Multivariate analysis showed that stage alone was statistically significant as the strongest predictor of survival. Conclusion: The results of our study validated ENETS/NANETS guidelines for staging and grading of rectal NETs in the US setting of a tertiary referral center. Staging according to ENETS/NANETS guidelines should be used in the treatment algorithm rather than size alone.

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Section: Discussionsupporting

confidence: 81%

“…Endoscopic ultrasound may be used to measure tumor size and depth [13]. Some studies suggest that malignant potential increases with increased tumor size and depth [4,14,15]. …”

Section: Introductionmentioning

confidence: 99%

Clinical and Prognostic Features of Rectal Neuroendocrine Tumors

Weinstock¹,

Ward

Harpaz

et al. 2013

Neuroendocrinology

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“…In 1 small trial, adults with CP and pain (n = 24) were randomized to an Iyengar yoga intervention or a control group. 59 Yoga decreased self-reported pain levels by 62% and selfreported use of pain medication by 36%, but no comparison to the control group was provided. Yoga participants reported significantly improved HRQoL (by SF-36), mood, and stress scores, compared with no change over time in controls.…”

Section: Yogamentioning

confidence: 99%

Outpatient Pain Management in Children With Chronic Pancreatitis

et al. 2022

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ObjectivesAlthough pain management is central to pediatric chronic pancreatitis (CP) care, no evidence-based guidelines exist. In this scoping systematic review, we sought promising strategies for CP pain treatment in children.MethodsWe systematically reviewed literature on pain management in children and adults with CP, and 2 conditions with similar pain courses: juvenile idiopathic arthritis and sickle cell disease.ResultsOf 8997 studies identified, 287 met inclusion criteria. There are no published studies of analgesic medications, antioxidants, dietary modification, integrative medicine, or regional nerve blocks in children with CP. In adults with CP, studies of nonopioid analgesics, pancreatic enzymes, and dietary interventions have mixed results. Retrospective studies suggest that endoscopic retrograde cholangiopancreatography and surgical procedures, most durably total pancreatectomy with islet autotransplant, improve pain for children with CP. Follow-up was short relative to a child's life. Large studies in adults also suggest benefit from endoscopic therapy and surgery, but lack conclusive evidence about optimal procedure or timing. Studies on other painful pediatric chronic illnesses revealed little generalizable to children with CP.ConclusionsNo therapy had sufficient high-quality studies to warrant untempered, evidence-based support for use in children with CP. Multicenter studies are needed to identify pain management “best practices.”

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“…60,61 In a 12 week study using yoga for patients with chronic pancreatitis amongst 24 patients, a reduction in need for pain medication, reduced pain perception and anxiety were noted suggesting some benefits. 62…”

Section: Other Measuresmentioning

confidence: 99%

Medical management of pain in chronic pancreatitis

Sharma¹

2014

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Chronic pancreatitis is a common disorder caused by various etiological factors. It usually manifests with abdominal pain and exocrine (steatorrhea, malnutrition) or endocrine insufficiency (diabetes mellitus). Abdominal pain is the dominant symptom in these patients. Medical, endoscopic and surgical modalities are available for therapy. This review focuses on the pharmacological approaches to manage pancreatic pain. Before embarking on medical management of pain it is prudent to exclude complications like pancreatic cancer, pseudocysts, inflammatory mass, biliary or duodenal obstruction which may contribute to abdominal pain. Pharmacological measures for pain relief include central analgesics, enzyme supplements and antioxidants. Other measures include endoscopic and surgical therapy which are not discussed here. Appropriate management of exocrine and endocrine insufficiency and successful control of diabetes are also important in the management of chronic pancreatitis.

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Yoga for rehabilitation in chronic pancreatitis

Cited by 19 publications

References 5 publications

Clinical and Prognostic Features of Rectal Neuroendocrine Tumors

Clinical and Prognostic Features of Rectal Neuroendocrine Tumors

Outpatient Pain Management in Children With Chronic Pancreatitis

Medical management of pain in chronic pancreatitis

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