Three-dimensional (3D) integration with interstrata vias has the potential of improving system performance while providing a platform for heterogeneous integration. Performance improvement in 3D integrated circuits (ICs) is mainly due to the reduction of interconnect length, which decreases interconnect delay and power consumption [1,2]. Small form factor is achieved in 3D ICs due to the stacking of active device layers one on top the other. A path for heterogeneous integration is realized if this stacking is done in a fashion that is back-end-of-line (BEOL) compatible, because interconnecting devices using fully fabricated wafers can reduce process incompatibilities.Approaches to 3D integration are often divided into die-level approaches and wafer-level approaches. Most often, the heterogeneous integration and small form factor advantages are obtained with die-level approaches; in addition, high performance and low manufacturing cost can be achieved with wafer-level approaches.CMP has permeated many aspects of IC processing but is particularly a dominant factor in BEOL interconnection. Copper damascene patterning has become the standard methodology for building a large number of interconnect layers in the vast majority of high-performance ICs. In 3D ICs, CMP is also critical in backside thinning, surface roughness reduction, and, in particular, feature topography control. Topography mitigation can particularly be a critical Microelectronic Applications of Chemical Mechanical Planarization, Edited by Yuzhuo Li