In this chapter, the tracking-control problems of multiple-integrator (MI) systems are investigated by using the ZG method. Several types of ZG controllers are presented for the tracking control of MI systems, e.g., triple-integrator (TI) systems. As an example, the design procedures of ZG controllers for TI systems with a linear output function (LOF) and a nonlinear output function (NOF) are presented. Corresponding theoretical analyses are given to guarantee the convergence performance of both z3g0 controllers and z3g1 controllers for TI systems. Computer simulations concerning the tracking control of MI systems with different types of output functions are further performed to substantiate the feasibility and efficacy of ZG controllers for tracking-control problem solving. Moreover, comparative simulation results for tracking control of MI systems with NOFs substantiate that the zmg1 controllers can effectively conquer the DBZ problem with m being the times of using the ZD method.