Zika virus: - a review of the main aspects of this type of arbovirosis

Dias, Ítala Keane Rodrigues; Sobreira, Cicera Luciana da Silva; Martins, Rosa Maria Grangeiro; Santana, Kelly Fernanda Silva; Lopes, Maria do Socorro Vieira; Joventino, Emanuella Silva; Viana, Maria Corina Amaral

doi:10.1590/0037-8682-0130-2018

Cited by 14 publications

(9 citation statements)

References 49 publications

(243 reference statements)

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“…The number of cases in Brazil peaked in 2016 with nearly 215,320 probable Zika cases [ 12 ], followed by 17,593 and 10,768 reported cases annually between 2017 and 2019 [ 13 , 14 ]. The occurrence of microcephaly and other congenital neurological malformations associated with ZIKV infections has been described worldwide [ 15 , 16 , 17 ], and the virus continues to be considered an important threat [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Vector Competence of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Brazil and New Caledonia for Three Zika Virus Lineages

et al. 2020

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Zika virus (ZIKV) has caused severe epidemics in South America beginning in 2015, following its spread through the Pacific. We comparatively assessed the vector competence of ten populations of Aedes aegypti and Ae. albopictus from Brazil and two of Ae. aegypti and one of Culex quinquefasciatus from New Caledonia to transmit three ZIKV isolates belonging to African, Asian and American lineages. Recently colonized mosquitoes from eight distinct sites from both countries were orally challenged with the same viral load (107 TCID50/mL) and examined after 7, 14 and 21 days. Cx. quinquefasciatus was refractory to infection with all virus strains. In contrast, although competence varied with geographical origin, Brazilian and New Caledonian Ae. aegypti could transmit the three ZIKV lineages, with a strong advantage for the African lineage (the only one reaching saliva one-week after challenge). Brazilian Ae. albopictus populations were less competent than Ae. aegypti populations. Ae. albopictus generally exhibited almost no transmission for Asian and American lineages, but was efficient in transmitting the African ZIKV. Viral surveillance and mosquito control measures must be strengthened to avoid the spread of new ZIKV lineages and minimize the transmission of viruses currently circulating.

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Section: Introductionmentioning

confidence: 99%

Vector Competence of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Brazil and New Caledonia for Three Zika Virus Lineages

et al. 2020

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“…9,10 The mosquito Aedes aegypti was most commonly accused of viral transmission, followed by sexual transmission, vertical transmission, and blood transfusion. 11 Its diagnosis is somewhat elusive. Blood and urine testing were proved most useful in acute diagnosis.…”

Section: Zika Virus Infectionsmentioning

confidence: 99%

Diagnostic Advances in Acute Viral Meningitis: Any Novelty for the Physician?

Karcıoğlu¹,

Yılmaz²

2018

Emerg Med Open J

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Acute viral meningitis (AVM) constitute an important cause of mortality and neurological morbidity within the last decades, in spite of all diagnostic and therapeutic advances in medical technology. Diagnostic procedures consist of lumbar puncture, hemoculture, complete blood cell count (including, leukocytes), procalcitonin, lactate and glucose to give an overall insight for disease; while polymerase chain reaction (PCR) and cerebrospinal fluid (CSF) analyses (urine reagent strips, glucose, protein, and microscopic examination) are used to diagnose herpetic meningeal involvement and most other viral infections affecting central nervous system (CNS). Findings in blood and CSF work-up after a clinical index of suspicion result in a high yield of diagnosis. Technological advances should be coupled with clinical findings to produce an accurate clinical management in the target population. This review is intended to analyze the epidemiology, clinical manifestation, findings on examination, and diagnostic tools to be utilized in patients suspected to have AVM in light of recent advances and research data, and to culminate up-to-date concept of AVM for primary care and emergency physicians.

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“…ZIKV often causes self-limited and mild illness commonly characterized by fever, rash, myalgia, arthralgia, and conjunctivitis (Dias et al, 2018). However, severe manifestations were associated with this disease, such as Guillain-Barré syndrome (Cao-Lormeau et al, 2016) and Zika congenital syndrome in infants (Brasil et al, 2016;Honein et al, 2017).…”

Section: Introductionmentioning

confidence: 99%