Zinc, Copper, Magnesium, and Calcium in Dialyzed and Nondialyzed

Mansouri, Karim

doi:10.1001/archinte.1970.00310010090007

Cited by 93 publications

(6 citation statements)

References 15 publications

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“…In spite of statements of the contrary [6], we found that the copper increased even during hemodialysis; the membranes liberated 44.44% of their copper content. The membranes used are made of cuprophan (cellulose and cuproammoniacal sol ution), which contains a certain amount of copper [8]; the mechanism of their liberation is not known although it might be influenced by the pH of the dialysis liquid and its tem perature.…”

Section: Discussioncontrasting

confidence: 89%

“…In patients on periodic hemodialysis our Bustamante/Mateo/De Paula de Pedro/Manchado basal values of copper and ceruloplasmin are similar to those of Mansouri et al [6], although other authors found higher values [3,7]. In spite of statements of the contrary [6], we found that the copper increased even during hemodialysis; the membranes liberated 44.44% of their copper content.…”

Section: Discussionsupporting

confidence: 84%

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Changes in Copper and Ceruloplasmin in Chronic Renal Insufficiency Treated by Hemodialysis and Peritoneal Dialysis

Bustamante

Mateo

Pedro

et al. 1978

Nephron

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Serum copper and ceruloplasmin as well as other parameters in 68 patients with chronic renal insufficiency were studied. It was found that chronic renal insufficiency increases neither the serum copper nor the serum ceruloplasmin. In the group on hemodialysis, there is a progressive increase of copper and ceruloplasmin in serum due to a liberation of 44.44% of the copper content of the membranes. In the group on periodic peritoneal dialysis, there is also an increase of serum copper during the dialysis. We do not have an explanation for this finding.

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Section: Discussioncontrasting

confidence: 89%

Section: Discussionsupporting

confidence: 84%

Changes in Copper and Ceruloplasmin in Chronic Renal Insufficiency Treated by Hemodialysis and Peritoneal Dialysis

Bustamante

Mateo

Pedro

et al. 1978

Nephron

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“…Piechota and colleges have reported insignificant differences between ESRD patients and healthy group for Zn and Cu plasma levels but Mg level was higher in patients than control individuals [15]. Mansouri and his cooperators reported normal concentrations of Zn in uremic patients [16]. However Ellis reported low serum and plasma Zn but Zn urinary level showed increase status [17].…”

Section: Discussionmentioning

confidence: 99%

Comparison of zinc, copper, selenium, magnesium, aluminium and lead blood concentrations in end-stage renal disease patients and healthy volunteers in Ahvaz, southwest of Iran

Shahbazian¹,

Absalan²,

Jalali³

et al. 2018

Russ Open Med J

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Introduction-Heavy metal storage and essential elements deficiency are two important issues in dialysis patients. Geographic region and dietary habits might affect essential trace elements concentration in body. Trace elements (TEs) status has not been studied previously in dialyzed patients in Ahvaz city. The aim of this study is to compare blood concentrations of six TEs between dialysis patients and normal group in Ahvaz, the center of Khuzestan province, in southwest of Iran. Material and Methods-We studied 33 end-stage renal disease (ESRD) patients and 33 normal cases. TEs assayed in serum samples, except lead, which assessed in whole blood. We used atomic absorption spectroscopy in this pressure. We used ANOVA and Tukey-HSD statistical analysis as well as binary logistic regression for calculating Odds ratio. Results-There was a significant difference between case and control groups for magnesium (Mg), aluminium (Al) and lead (Pb) (P<0.05), but there was not a significant difference for copper (Cu) and selenium (Se) (P>0.05). Zinc (Zn) level change was not significant. Al and Pb level increased after dialysis but Mg level decreased. All calculated Odds ratios were weak for all investigated trace elements. Different results published about TEs level in ESRD patients. Increase in TEs level in case group may be as a result of chronic poisoning through dialysis and after dialysis hemoconcentration, respectively. In order to understand the exact reason of this observation we need comprehensive and monitored studies. TEs disturbances in Ahvaz ESRD patients imply the importance of periodically studies. Conclusion-The most important interpretations and suggestions of this study is that the TEs level is different among different population. Then, Iranian health-providers should consider to TEs assessment in both healthy and patient cases. Periodical measurement of TEs is essential for ESRD patients and it can be helpful in preventing TEs deleterious effects.

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“…The decreased gustin levels may also relate to an inability to absorb, transport, or store zinc. Approximately one-quarter of patients with taste and smell dysfunction have been found to exhibit zinc-malabsorption (31), and patients with chronic renal disease exhibit hypogeusia, hypogonadism, and other signs of zinc deficiency (32)(33)(34)(35)(36)(37)(38), which have been corrected with exogenous zinc therapy in controlled clinical trials (36)(37)(38).…”

Section: Methodsmentioning

confidence: 99%