Zinc oxide nanoparticles synthesized using Oldenlandia Umbellata leaf extract and their photocatalytic and biological characteristics

Shahanaz, L.; Shalini, A.S. Stella

doi:10.1016/j.jics.2023.100917

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…This means that the ZnONPs negative charge is within the stable range, reinforcing their suitability for various applications. Interestingly, previous research involving [6, 35,38,39,40,41], also yielded ndings consistent with the results obtained in the present study.…”

Section: Ftir Of Rc@znonpssupporting

confidence: 93%

“…It is important to note, however, that none of the tested samples showed a degree of inhibition greater than that of Amp-B, a known antifungal agent. This data is consistent with previous studies [2,5,7,21,32,39,41,42,50,51,52,53] that indicate ZnONPs interact with fungi and their hyphae to impede fungal growth and produce Reactive Oxygen Species (ROS). This current study's outcomes parallel those of previous investigations conducted which showcased a signi cant and dose-dependent antifungal activity, a correspondence that further encourages the credibility of the present ndings.…”

Section: Antibacterial Assay Of Rc@znonpssupporting

confidence: 93%

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Rhynchosia capitata driven bioproduction of Zinc oxide nanoparticles, characterization and multifaceted therapeutic applications

Ullah,

Iqbal,

Abbasi

et al. 2024

Preprint

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The current study aimed to formulate zinc oxide nanoparticles (ZnONPs) employing an aqueous extract derived from Rhynchosia capitata (RC). Utilizing several spectroscopic methods (UV-visible spectroscopy, XRD, FTIR, SEM, EDX, DLS), the synthesis of ZnONPs was evaluated. ZnONPs have a mean crystallite size of about 32.15 nm, as determined by the Scherrer equation. Moreover, in vitro, biological assessments showed notable therapeutic potential. Furthermore, the disc diffusion method was precisely employed with antibacterial and antifungal properties across a range of concentrations (100–1500 µg/ml). Among the bacteria, B. subtilis displayed a prominent inhibition zone, measuring 24 mm at 1500 µg/ml. Similarly, susceptible fungal strains demonstrated a zone of inhibition measuring 29 mm. Antioxidant potentials were determined using different assays. The radical-scavenging capabilities were quantified using a DPPH assay and revealed a significant result of 73%. Further, reducing power was calculated and found to be 69 ± 1.77%, and the total antioxidant capacity was found to be 88 ± 4.8. Brine shrimps cytotoxicity assay was performed and displayed an LC50 value of 2.20 µg/mL, affirming biocompatibility. The biocompatibility potential of ZnONPs was determined against red blood cells, HEK, and VERO cell lines at different concentrations to confirm their biosafety and biocompatibility. An alpha-amylase (AA) inhibition assay was performed and showed a percent inhibition of 70%. Particularly noteworthy was the ZnONPs efficacy against (Hep-2 liver) cancer cells (IC50:44.90). The ZnONPs exhibited promising non-toxic attributes and displayed substantial potential for diverse biological applications in various domains. The outcomes of this study are anticipated to contribute valuable insights and open new avenues for further research and development of ZnONPs in a multitude of biomedical applications.

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Section: Ftir Of Rc@znonpssupporting

confidence: 93%

Section: Antibacterial Assay Of Rc@znonpssupporting

confidence: 93%

Rhynchosia capitata driven bioproduction of Zinc oxide nanoparticles, characterization and multifaceted therapeutic applications

Ullah,

Iqbal,

Abbasi

et al. 2024

Preprint

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“…Moreover, FeONPs have found immense applications in environmental remediation as catalysts for the degradation of organic pollutants and in energy storage as electrode materials for batteries and supercapacitors (Hammad et al, 2022;Saied et al, 2022). While, TiO 2 NP and ZnNPs offer unique properties of ultraviolet absorption and fluorescence, which make them useful in biomedicine as imaging materials, fabrication of sunscreen UVprotective cosmetics, and in electronics as optoelectronic devices (Shahanaz and Shalini, 2023). The BMNPs offer a sustainable and eco-friendly alternative to traditional chemical methods, which produce toxic MNPs.…”

Section: Introductionmentioning

confidence: 99%

Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products

Kumar

Shah

Jayeoye

et al. 2023

Front. Nanotechnol.

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Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs have several advantages over chemically synthesized ones due to their eco-friendly synthesis regimen, sustainability, biocompatibility, and diverse multifarious biomedical applications. Moreover, the superior cytocompatibility and stability due to the capping layer over metallic nanoparticles (MNPs), reduces the like hood of toxicity and side effects, making them a safer alternative to traditional drug delivery methods. Among several promising applications of BMNPs, their antibacterial activity, analytical sensing of heavy metals, and their roles in food preservations have been widely explored. In addition, to drug delivery and imaging, BMNPs have also been investigated for therapeutic activity such as antimicrobial efficacy against the skin and soft tissue nosocomial pathogens and targeting cancer cells in cancer therapy. The present review bestows several characterization techniques involved with MNPs and compressive aspects of the biogenic synthesis of MNPs using agricultural and biological materials, which reduces the cost of synthesis and minimizes the use of hazardous chemicals. The review also focuses on the multifold applications of BMNPs including biomedical, analytical, preservation of food, and in other consumable goods with toxicological aspects.

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Phytochemistry, pharmacology, and medical uses of Oldenlandia (family Rubaceae): a review

Al-Shuhaib,

Al-Shuhaib

2023

Naunyn-Schmiedeberg's Arch Pharmacol

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Zinc oxide nanoparticles synthesized using Oldenlandia Umbellata leaf extract and their photocatalytic and biological characteristics

Cited by 4 publications

References 26 publications

Rhynchosia capitata driven bioproduction of Zinc oxide nanoparticles, characterization and multifaceted therapeutic applications

Rhynchosia capitata driven bioproduction of Zinc oxide nanoparticles, characterization and multifaceted therapeutic applications

Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products

Phytochemistry, pharmacology, and medical uses of Oldenlandia (family Rubaceae): a review

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