ZnO Nanoparticles Applied to Bioimaging and Drug Delivery

Xiong, Hongwei

doi:10.1002/adma.201301732

Cited by 499 publications

(278 citation statements)

References 70 publications

(75 reference statements)

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“…Direct electrospinning of titania nanofibers on a conducting electrode was used to construct a cholesterol biosensor ( Figure 14 describes the synthesis and application of nanofibers as an enzymatic biosensor) that can detect esterified cholesterol from human blood with excellent sensitivity (181.6 μA/mg·dL -1 /cm 2 ) and rapid detection (20 s) [105]. Additionally, metal oxide nanofibers have found huge importance in immunolabeling, cell and molecular bioimaging, biosensing, treatment of tumor cells, soil nutrient sensing, and numerous photosensitive applications [188][189][190][191][192]. …”

Section: Other Applicationsmentioning

confidence: 99%

Recent Advances in the Synthesis of Metal Oxide Nanofibers and Their Environmental Remediation Applications

Mondal

2017

Inventions

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Recently, wastewater treatment by photocatalytic oxidation processes with metal oxide nanomaterials and nanocomposites such as zinc oxide, titanium dioxide, zirconium dioxide, etc. using ultraviolet (UV) and visible light or even solar energy has added massive research importance. This waste removal technique using nanostructured photocatalysts is well known because of its effectiveness in disintegrating and mineralizing the unsafe organic pollutants such as organic pesticides, organohalogens, PAHs (Polycyclic Aromatic Hydrocarbons), surfactants, microorganisms, and other coloring agents in addition to the prospect of utilizing the solar and UV spectrum. The photocatalysts degrade the pollutants using light energy, which creates energetic electron in the metal oxide and thus generates hydroxyl radical, an oxidative mediator that can oxidize completely the organic pollutant in the wastewater. Altering the morphologies of metal oxide photocatalysts in nanoscale can further improve their photodegradation efficiency. Nanoscale features of the photocatalysts promote enhance light absorption and improved photon harvest property by refining the process of charge carrier generation and recombination at the semiconductor surfaces and in that way boost hydroxyl radicals. The literature covering semiconductor nanomaterials and nanocomposite-assisted photocatalysis-and, among those, metal oxide nanofibers-suggest that this is an attractive route for environmental remediation due to their capability of reaching complete mineralization of organic contaminants under mild reaction conditions such as room temperature and ambient atmospheric pressure with greater degradation performance. The main aim of this review is to highlight the most recent published work in the field of metal oxide nanofibrous photocatalyst-mediated degradation of organic pollutants and unsafe microorganisms present in wastewater. Finally, the recycling and reuse of photocatalysts for viable wastewater purification has also been conferred here and the latest examples given.

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Section: Other Applicationsmentioning

confidence: 99%

Recent Advances in the Synthesis of Metal Oxide Nanofibers and Their Environmental Remediation Applications

Mondal

2017

Inventions

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“…We observe red defect emissions under 532 nm excitation at room temperature, where the defects exhibit blinking characteristics with occasional photostability. Furthermore, ZnO NPs were also removed from the silica substrate, and characterised again, with the motivation of using ZnO as a promising candidate for bioimaging [51]. We show that these ZnO NPs were able to be taken up by human epidermal keratinocyte cells, resulting in photostable emission from the defects above cellular autofluorescence.…”

Section: Introductionmentioning

confidence: 99%

Room-temperature single-photon emission from zinc oxide nanoparticle defects and their in vitro photostable intrinsic fluorescence

et al. 2016

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Zinc oxide (ZnO) is a promising semiconductor that is suitable for bioimaging applications due to its intrinsic defect fluorescence. However, ZnO generally suffers from poor photostability. We report room-temperature single-photon emission from optical defects found in ZnO nanoparticles (NPs) formed by ion implantation followed by thermal oxidation in a silica substrate. We conduct a thorough investigation into the photophysics of a particularly bright defect and identify other single emitters within the NPs. Photostability was observed when the NPs were removed from the growth substrate and taken up by skin cells for in vitro imaging.

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“…However, the surface of ZnO nanoparticles needs to be modified to protect them in biological systems as they can be dissolved easily in water and acidic solutions. Also to use ZnO nanoparticles for fluorescence in imaging, the nanoparticles need to be doped as the ZnO bandwidth is in the UV region and UV light cannot penetrate tissue and is also harmful to cells and tissue [203][204][205][206].…”

Section: Metal Oxide Nanoparticlesmentioning

confidence: 99%