ZnO Nanoparticles Embedded on a Reduced Graphene Oxide Nanosheet (ZnO−NPs@r‐GO) as a Proficient Heterogeneous Catalyst for a One‐Pot A³‐Coupling Reaction

Abstract

This study reports a simple and facile route for the synthesis of ZnO nanoparticles (ZnOÀ NPs) decorated on reduced graphene oxide nanosheet (ZnOÀ NPs@r-GO) as a heterogeneous catalyst and tested over multicomponent one-pot A 3 -coupling reaction. The reduction of graphene oxide with the anchoring of ZnOÀ NPs on the r-GO nanosheet was observed through the Xray diffraction patterns, Raman, FTIR, and XPS results of the ZnOÀ NPs@r-GO sample. ZnOÀ NPs (average particle size of 3.4 � 1.5 nm) with uniform size distribution over r-GO nanosheet were substantiated through HRTEM analysis. Impressively, ZnOÀ NPs@r-GO significantly used for A 3 -coupling reaction with different aromatic aldehydes, active methylene compounds, and urea and under the optimized reaction conditions gave exceptional activity to produce synthetically valuable 3,4dihydropyrimidinones products (possessing diverse therapeutic and pharmacological properties) i. e. 97 % isolated yield of the product. In addition, excellent reusability up to 4 repeated cycles are the key advantages of the present catalyst used for this multicomponent A 3 -coupling reaction.

DFT stimulation and experimental insights of chiral Cu(ii)–salen scaffold within the pocket of MWW-zeolite and its catalytic study

“…In summary, these complexes have demonstrated high reusability and stability in zeolite-Y, making them attractive for industrial applications. In light of our previous efforts, [35][36][37][38] herein we report for the first time the encapsulation of chiral Cu(II)-salen complexes inside MWW-framework zeolite pores and tested for one-pot multicomponent Biginelli reaction in liquid phase. To comprehend the nature of the structural and electronic changes that occur in complexes under the influence of the MWW zeolite framework, a density functional theory (DFT) approach has been applied.…”

Atomically Precise Cun(n=3, 6 and 11) Nanocatalysts for Alkyne‐Haloalkane‐Amine (AHA) Coupling Reaction

“…[1][2][3] Different propargylamines are usually synthesized by the three-component coupling method (A 3 coupling) of amine, alkyne and aldehyde. [4][5][6][7][8][9][10][11][12][13][14] In AHA coupling reactions, halomethane is an inexpensive and readily available industrial solvent as a methylene fragment for replacing aldehydes. However, highly active catalysts that can catalyze AHA coupling reactions are still limited.…”

“…Propargylamine is the key intermediates in several kinds of chemicals and biologically active molecules such as Parkinson's disease [1–3] . Different propargylamines are usually synthesized by the three‐component coupling method (A 3 coupling) of amine, alkyne and aldehyde [4–14] . In AHA coupling reactions, halomethane is an inexpensive and readily available industrial solvent as a methylene fragment for replacing aldehydes.…”