Zur Biologie der Fette IX: Die Resorption von Konjuenölen und die Verteilung der Konjuensäuren im Fett der Versuchstiere (1. Mitt. über die Biochemie der Konjuensäuren)

Abstract

Das die Parinarsaure enthaltende Sameno1 von Impatiens glanduligera ist nicht toxisch. Seine Resorption kann im Tierversuch an Hand des UV-Spektrums verfolgt werden. Bei einmaliger Verabreichung an Ratten und Kaninchen erscheint die Parinarsaure zunachst im mesenterialen, dann im perirenalen, schlieRlich im subkutanen und perigenitalen Fettgewebe. Bei Iangerer Fiitterung kehrt sich diese Reihenfolge und damit die ,,turnover rate" uin. Biology of Fats IX: The Resorption of Conjugated Oils and the Distribution of Conjugated Fatty Acids in the Fat of some Experimental-Animals (1st. communication: The Biochemistry of Conjugated Fatty Acids)The seed oil of Impatiens glanduligera, which contains parinaric acid, is not toxic. It is possible to follow the resorption of this oil with the help of UV-analysis in case it is fed to the animals. On administering this oil only once to the rats and the rabits, parinaric acid appears first in the mesenterial, then in the perirenal and last of all in the subcutaneous and perigenital fatty tissues. On being fed for rather a longer period, the above order of the appearance of this acid in various tissues and with that the turnover rate is reversed.

Hydrogenated oils and polyunsaturated fatty-acid isomers in nutrition

“…They suggested that this retardation may have been due to an unfavourable effect of the conjugated acids as such, or of a high dietary content of fat without EFA. Recently, Kaufmann & Dransfeld (1960) studied the absorption and distribution in the tissues of the seed oil of Impatiens glanduligera which contains parinaric acid (a C,, conjugated tetraenoic acid). T h e oil was found to be non-toxic to rats and rabbits.…”