Zur Entstehung der Kokzidienknoten in der Leber von Kaninchen

Phylogenetic relationships amongEimeriaspp. (Apicomplexa, Eimeriidae) infecting rabbits: evolutionary significance of biological and morphological features

“…The whole rabbit-specific fauna is relatively heterogeneous in respect to oocyst morphology, location within host or pathogenicity (Pellérdy, 1965; Coudert et al 1995; Eckert et al 1995). While 10 of the rabbit Eimeria species develop in the host intestine, E. stiedai parasitizes the epithelium of biliary ducts (Metzner, 1903; Minning, 1936; Rutherford, 1943). Some species are highly pathogenic, causing apathy, inapetency, severe growth depression, tympany, diarrhoea or even mortality ( E. stiedai , E. flavescens , E. intestinalis ); others express mild ( E. magna , E. piriformis , E. irresidua , E. media ) or low ( E. coecicola , E. perforans , E. exigua , E. vejdovskyi ) pathogenicity for their hosts (Pellérdy, 1965; Coudert et al 1979; Licois and Mongin, 1980; Licois and Coudert, 1982; Vítovec and Pakandl, 1989; Coudert et al 1995; Pakandl and Coudert, 1999).…”

The route of migration of Eimeria stiedae (Lindemann, 1865) sporozoites between the duodenum and bile ducts of the rabbit

“…Comparison of the liver sections from material taken at 72, 84 and 96 h postinfection with the controls failed to show any conspicuous lymphocytic infiltration of the periportal region as described by Minning (1936). In some sections there was an increase in the number of lymphocytes round the bile ductules.…”

“…There is a period in the life-cycle of Eimeria stiedae in which the whereabouts of the sporozoites is not known. This period has been variously stated to last for 96 h after infection (Minning, 1936;Rose, 1958) and 72 h (Davies, Joyner & Kendall, 1962), and it is assumed that during the greater part of this period the sporozoite is migrating from the duodenum to the bile duct epithelium. Smetana (1933 a) ruled out the possibility that the sporozoites migrated up the bile ducts to the bile duct epithelium, and suggested that they must migrate via the blood or lymph.…”

“…The route by which the sporozoites of Eimeria stiedae (Lindemann, 1865) reach the bile duct epithelium has not been elucidated, though the rest of the life-cycle has been worked out (von Wasielewski, 1904;Reich, 1913;Smetana, 1933a, 6;Minning, 1936;Rose, 1958). It was first believed that the oocyst travelled up the bile duct where it excysted and infected the bile duct epithelium directly.…”