Zur Frage der Heparin-Beteiligung bei der anaphylaktischen Histaminase-Freisetzung des Meerschweinchens

After intravenous injection of heparin (in aniounts related to the body‐weight) thc blood plasma diamine oxidase(DAO‐) activity increased transiently in all vertebrates studied (cod, frog, fowl, mouse, white rat, golden hamster, guinea‐pig, rabbit, cat, dog, goat, sheep and cow). The DAO‐response to heparin varied strongly between the species. Often with a bi‐phasic ascent, it showed a maximum (within a few minutes to about one hour) and then decreased, often in a “monoexponential” fashion, in the course of the next few hours. In anodons no significant DAO‐activity was found.—The biological significance of the heparin effect upon DAO is discussed with special reference to the coexistence of heparin and histamine in the mast cells.

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The Effect of Heparin on Diamine Oxidase and Lipoprotein Lipase in Human Lymph and Blood Plasma

Dahlbäck

Hansson

Tibbling

et al. 1968

Scandinavian Journal of Clinical and Laboratory Investigation

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Zur Frage der Heparin-Beteiligung bei der anaphylaktischen Histaminase-Freisetzung des Meerschweinchens

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Hemmung der anaphylaktischen histaminasefreisetzung durch protamin beim meerschweinchen

Hemmung der anaphylaktischen histaminasefreisetzung durch protamin beim meerschweinchen

Diamine Oxidase in Blood Plasma in Some Vertebrates and Anodonta cygnea before and after Injection of Heparin

The Effect of Heparin on Diamine Oxidase and Lipoprotein Lipase in Human Lymph and Blood Plasma

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