Zur Gaschromatographie von Vitamingemischen

Janecke, H.; Voege, H.

doi:10.1007/bf00602673

Cited by 10 publications

(1 citation statement)

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“…Janecke and Voege (12) are often quoted in literature reviews regarding their studies of vitamin A. The cited report is a very short communication containing no research data per se, and indicates only that the fat-soluble vitamins can be determined on a 3% SE-30 column temperature programed from 100 to 270 C and on a 2.5% SE-30 column at 250 C.…”

Section: Vitami N Amentioning

confidence: 99%

Gas chromatography of the fat‐soluble vitamins: A review

Sheppard

Prosser

Hubbard

1972

J Americ Oil Chem Soc

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The application of gas liquid chromatography (GLC) as an analytical tool for the determination of the fat-soluble vitamins A, D, E and K has yet to be utilized to its full potential. A review of the published work of many researchers in this field is presented. GLC methods to measure the vitamin A isomers have not been developed to any appreciable practical extent. Liquid liquid chromatography might well be the technique of choice. In the field of vitamin D there are indications that a practical GLC analysis is feasible for pharmaceutical preparations. The GLC applications for vitamin E are diverse, well defined and generally widely accepted in research laboratory situations and for regulatory and quality control usage. Vitamins K 1 and K 2 have been measured with limited success in a few research laboratories, but the GLC methods have not developed on a practical basis. However GLC is used for measuring vitamin K 3 (menadione and menadione sodium bisulfite) on a fairly routine basis in quality control laboratories.

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Section: Vitami N Amentioning

confidence: 99%

Gas chromatography of the fat‐soluble vitamins: A review

Sheppard

Prosser

Hubbard

1972

J Americ Oil Chem Soc

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Biotin

Outten¹

2000

Kirk-Othmer Encyclopedia of Chemical Technology

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Biotin is a water‐soluble B complex vitamin originally isolated from a variety of natural sources. In biological systems, biotin functions as a cofactor for enzymes involved in carboxylation reactions. A lack of biotin results in deficiency diseases in humans and animals. Daily intakes of biotin are recommended in the maintenance of optimal health. Several synthetic pathways to biotin have been developed since its stereochemical determination. The modern industrial synthesis is based on work done by researchers in the late 1940s. Since this work, industrial research has been directed toward process improvements in the basic methodology, particularly in the area of methods to form optically pure d ‐lactone. Research has also been directed toward elucidation of the biosynthetic pathway to biotin. Various microorganisms have been evaluated for use in biotin synthesis via fermentation. Recently, a number of patents have appeared on the synthesis of biotin using biotechnology. Several analytical methods, including microbiological, chemical, and chromatographic assays, are used to determine biotin levels in food and body fluids.

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