Zur intestinalen Absorption von Zink während der Gravidität und Laktation

Fj, Schwarz; Kirchgeßner, M.; Sy, Sherif

doi:10.1007/bf01852123

Cited by 13 publications

(3 citation statements)

References 21 publications

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“…The excess of zinc absorbed during pregnancy is stored in body pools ("Super retention") and is used for the consecutive lactation period. The rate of zinc absorbed during lactation depends on the amounts of zinc stored in the body during pregnancy (Davis and Williams 1977, Schwarz et al 1981).…”

Section: Absorption In Mammalsmentioning

confidence: 99%

Zinc

and¹,

Eder²

2004

Elements and Their Compounds in the Environment

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Section: Absorption In Mammalsmentioning

confidence: 99%

Zinc

and¹,

Eder²

2004

Elements and Their Compounds in the Environment

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“…Für Mangan steigt dabei nicht nur die ge samte Retention, sondern auch die Mn-Konzentration in der Leber und im Ganzkörper ist gegenüber den nichtgraviden Kontrollratten eindeutig erhöht [21]. Dies überrascht, da Absorptionsänderungen für Mangan auf grund einer unterschiedlichen Versorgung, des Alters oder der Trächtigkeit stets weniger deutlich ausgeprägt sind als für das Spuren element Zink [18][19][20] …”

Section: Introductionunclassified

Absorptionsveränderungen von Mangan während Gravidität und Laktation

Kirchgeßner¹,

Sherif²,

Schwarz³

1982

Ann Nutr Metab

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Model studies were conducted using isolated everted sacs of small intestines of rats to test the absotion of manganese during pregnancy and lactation. The intestinal transfer of manganese to the serosal solution and the uptake of manganese into the intestinal wall were measured. The results agree well and yield a comparable pattern of absorption. The Mn absorption rises only slightly in the first and second third of gestation (6th and 12th days of gestation). In the third part of pregnancy (18th day), however, three times more manganese is absorbed compared to the nonpregnant, nonlactating control animals (p < 0.001). The Mn transfer and uptake decrease distinctly at the day of birth (20th day of gestation and 1st day of lactation) but only for this short period. The absorption increases again significantly (p < 0.05) on the 3rd, 5th and 8th days of lactation, respectively, while it decreases at the end of lactation (21st day of lactation) to the level of the controls. Reasons for this pattern are discussed.

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“…Using the duodenal loop technique, it has been shown that zinc absorption increased after pregnancy termination (4), and other authors (21) also found that the zinc uptake and transfer across isolated everted intestinal sacs from pregnant rats was significantly higher than that of control animals during the last third of gestation.…”

mentioning

confidence: 99%

Effects of folic acid and amino acids supplementation on zinc intestinal absorption in the progeny of ethanol-treated rats

Tavares

Carreras

Gómez‐Tubío

et al. 2000

J. Physiol. Biochem.

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This study was designed to examine the effects of supplementation with folic acid and amino acids in dams that consumed ethanol during gestation and lactation to see whether there is an improvement in the intestinal absorption of zinc in pup rats on the 21st day after birth. The rats were randomized into two groups: Ethanol-rats (EG) were administered ethanol during the pregnancy and lactation periods; the ethanol-folic acid group (EFG) received a folic acid and amino acid supplement concomitantly with ethanol administration during pregnancy and lactation. The dams were mated to obtain the first offspring. Two sets of experiments were performed on the offspring at 21 days after birth. In general, in the first set, jejunal zinc absorption in the offspring of EG and EFG groups showed a gradual increase along with increased perfusion time at all assayed concentrations. Jejunal zinc absorption expressed as nmol/intestinal surface was higher in the ethanol-folic acid group than in ethanol animals at all assayed concentrations except at 25 microM concentration. In the second set of experiments, distal ileum zinc absorption in the offspring of ethanolfolic acid dams showed a significant increase at all concentrations tested. These results indicate that supplementation of folic acid and amino acids to dams that consume ethanol during gestation and lactation increase serum and milk zinc levels, although the zinc ingestion is lower. In pups of the supplemented dams, the jejunal and ileal absorption of zinc increased; as a consequence, the serum zinc levels increased. The activity of alcohol dehydrogenase, a metaloenzyme dependent on zinc levels, also increased.

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Zur intestinalen Absorption von Zink während der Gravidität und Laktation

Cited by 13 publications

References 21 publications

Zinc

Zinc

Absorptionsveränderungen von Mangan während Gravidität und Laktation

Effects of folic acid and amino acids supplementation on zinc intestinal absorption in the progeny of ethanol-treated rats

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Zur intestinalen Absorption von Zink während der Gravidität und Laktation

Cited by 13 publications

References 21 publications

Zinc

Zinc

Absorptionsver&auml;nderungen von Mangan w&auml;hrend Gravidit&auml;t und Laktation

Effects of folic acid and amino acids supplementation on zinc intestinal absorption in the progeny of ethanol-treated rats

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Absorptionsveränderungen von Mangan während Gravidität und Laktation