Zur Kurzzeitfluktuation der Lichtunterschiedsempfindlichkeit im Randbereich glaukomatöser Gesichtsfelddefekte

Abstract

Using profile program F-4 of the Octopus 201 computerized perimeter, retinal light sensitivity and threshold short-term fluctuations were studied in 15 eyes of 15 patients with glaucomatous field defects, with a resolution of 1.5 degrees. The scotomata were verified with programs 33 and 34 of the Octopus 201. Control profiles, either at identical locations in the healthy fellow eye or in areas showing no glaucomatous changes, were used to compare focal fluctuation in the vicinity of the scotoma. At the borders of the scotomata, between 20 degrees and 30 degrees eccentricity, a significant increase in short-term fluctuation of retinal sensitivity was found. This change in short-term fluctuation decreased with increasing distance from the field defect. Significantly greater short-term fluctuations were also detected in border-area measurements of scotomata located between 0 and 10 or 10 and 20 degrees of eccentricity.

New visual field indices of disharmony for early diagnosis of glaucoma, alone or associated with conventional parameters

“…In some cases, initial perimetric defects should manifest as functional instability; [17][18][19][20] in others, as an observable loss of sensitivity, or both simultaneously. A comparison that can serve as an example is the level of water in a sink.…”

“…14,15 However, simultaneous study of both factors could help determine the risk of progression. 16 But early signs of impaired function, such as increased fluctuation, [17][18][19][20] can also be found in conventional whiteon-white perimetry, although they are not always easy to detect, especially when they require long-duration examinations which influence the very parameter being investigated. In any case, the inclusion of more sensitive criteria to promote early diagnosis must be done without reducing specificity, and reliance on only one of them in isolation is unlikely to achieve that.…”

Dokumentation glaukomatöser Gesichtsfeldverläufe bei schwellennah-überschwelliger Perimetrie

“…Weber und Krieglstein (12) zeigten mit ihrer ,,Graphischen Analyse topographischer Trends", daB im Bereich eines Skotoms stabile, d. h. unveranderte Zonen in unmittelbarer Nachbarschaft neben Arealen mit Veranderungen zu erkennen sind. Auf das enge Nebeneinander von stabilen, in diesem Fall absoluten Skotomen und veranderlichen Elementen wie verstarkten Kurzzeit-Fluktuationen weist ebenfalls die Arbeit von Dieste/horst und Krieg/stein (2) bin.…”