Zur Pathogenese der Tracheopathia chondro-osteoplastica

Hempel, Kay; Glaser, A.

doi:10.1007/bf00955181

Cited by 20 publications

(8 citation statements)

References 11 publications

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“…After careful consideration of the evidence thistheory was rejected by Dalgaard (1947) and by Hempel and Glaser (1958).…”

Section: Discussionmentioning

confidence: 99%

“…Metabolic disturbance Hempel and Glaser (1958) postulated that the bony islet development was due to metabolic and local inflammatory disturbances, leading to acidosis, hyaline swelling, transformation to cartilage, and then bone formation. This armchair speculation has been rejected by Spencer (1962), who emphasizes that there is no alteration in calcium or phosphorus metabolism and no connexion with pulmonary calcinosis.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Tracheobronchopathia osteoplastica: Its relationship to primary tracheobronchial amyloidosis

Sakula

1968

Thorax

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“…After careful consideration of the evidence thistheory was rejected by Dalgaard (1947) and by Hempel and Glaser (1958).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Tracheobronchopathia osteoplastica: Its relationship to primary tracheobronchial amyloidosis

Sakula

1968

Thorax

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“…Dies mag der Grund dafür sein, dass die TO in früheren Jahren vornehmlich von Pathologen zufällig im Rahmen von Sektionen gesehen und beschrieben wurde [3, 4, [15]; Tukiainen et al [35]; Vilkmann u. Keistinen [36]), und es auch in Finnland selbst eine geographische Häufung im Nordosten gibt [36]. Eine hereditäre Prädisposition in dieser "genetisch isolierten Region" und das kalte Klima mit entsprechend hoher Inzidenz von bronchopulmonalen Infekten, die einen Kofaktor in der Pathogenese darstellen sollen [13], wurden als Ursache dieser regionalen Häufung vermutet.…”

Section: Diskussion Epidemiologieunclassified

Klinische Aspekte der Tracheopathia osteoplastica

Neumann

Kasper

Schultz-Coulon

2001

HNO

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Tracheopathia osteoplastica is a rare condition of the tracheobronchial tree characterized by the formation of multiple osseous or cartilaginous submucosal nodules which protrude into the lumen. Clinical features, pathological-anatomical, and radiological findings are described and discussed on the basis of three recent cases and a literature review.Two female patients (age 56 and 62 years) and one male (age 44 years) presented with recurrent tracheobronchitis, a "difficult intubation" at the time of an emergency situation requiring tracheostomy. The diagnosis was confirmed by tracheoscopy. CT scans showed radiodense nodular thickening of the tracheal wall compromising the lumen in all patients, whereas plain chest radiography revealed scalloped linear calcification in only one case. Histologically the nodules consisted of lamellar-type bone covered by normal mucosa. None of the patients needed therapeutic measures as there was no impairment of ventilatory function. The long-term observations (>15 years) of a few authors suggest that the disease is of benign course and does not deteriorate.

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“…Hempel and Glaser (1958), in their series of eight cases, postulated acidosis arising from metabolic or local inflammatory disturbances as a cause of hyaline swelling, which then progresses to cartilage or bone formation.…”

Section: Case Reportmentioning

confidence: 99%